Systematic Reviews in Health Research
Explore the cutting-edge of systematic reviews in healthcare
In this Third Edition of the classic Systematic Reviews textbook, now titled Systematic Reviews in Health Research, a team of distinguished researchers deliver a comprehensive and authoritative guide to the rapidly evolving area of systematic reviews and meta-analysis. The book demonstrates why systematic reviews—when conducted properly—provide the highest quality evidence on clinical and public health interventions and shows how they contribute to inference in many other contexts. The new edition reflects the broad role of systematic reviews, including:
Twelve new chapters, covering additional study designs, methods and software, for example, on genetic association studies, prediction models, prevalence studies, network and dose-response meta-analysis Thorough update of 15 chapters focusing on systematic reviews of interventions Access to a companion website offering supplementary materials and practical exercises (www.systematic-reviews3.org)
A key text for health researchers, Systematic Reviews in Health Research is also an indispensable resource for practitioners, students, and instructors in the health sciences needing to understand research synthesis.
Edited by:
Matthias Egger (University of Bern Bern Switzerland; University of Cape Town South Africa),
Julian P. T. Higgins (Bristol Medical School,
University of Bristol,
Bristol,
UK),
George Davey Smith (University of Bristol,
Bristol,
UK)
Imprint: BMJ Books
Country of Publication: United Kingdom
Edition: 3rd edition
Dimensions:
Height: 257mm,
Width: 178mm,
Spine: 36mm
Weight: 1.406kg
ISBN: 9781405160506
ISBN 10: 1405160500
Pages: 608
Publication Date: 26 May 2022
Audience:
College/higher education
,
Professional and scholarly
,
Further / Higher Education
,
Undergraduate
Format: Hardback
Publisher's Status: Active
Preface xix Tribute xxi List of Contributors xxviii About the Companion Website xxxiii CHAPTER 1 Systematic Reviews in Health Research: An Introduction 1 Matthias Egger, Julian P.T. Higgins, and George Davey Smith PART I Principles and Procedures 17 CHAPTER 2 Principles of Systematic Reviewing 19 Julian P.T. Higgins, George Davey Smith, Douglas G. Altman, and Matthias Egger CHAPTER 3 Identifying Randomized Controlled Trials 36 Julie Glanville and Carol Lefebvre CHAPTER 4 Assessing the Risk of Bias in Randomized Trials 55 Matthew J. Page, Douglas G. Altman, and Matthias Egger CHAPTER 5 Investigating and Dealing with Publication Bias and Other Reporting Biases 74 Matthew J. Page, Jonathan A.C. Sterne, Julian P.T. Higgins, and Matthias Egger CHAPTER 6 Managing People and Data 91 Eliane Rohner, Julia Bohlius, Bruno R. da Costa, and Sven Trelle CHAPTER 7 Reporting and Appraisal of Systematic Reviews 109 Larissa Shamseer, Beverley Shea, Brian Hutton, and David Moher PART II Meta-Analysis 129 CHAPTER 8 Effect Measures 131 Julian P.T. Higgins, Jonathan J. Deeks, and Douglas G. Altman CHAPTER 9 Combining Results Using Meta-Analysis 159 Jonathan J. Deeks, Richard D. Riley, and Julian P.T. Higgins CHAPTER 10 Exploring Heterogeneity 185 Julian P.T. Higgins and Tianjing Li CHAPTER 11 Dealing with Missing Outcome Data in Meta-Analysis 204 Ian R. White and Dimitris Mavridis CHAPTER 12 Individual Participant Data Meta-Analysis 220 Mark C. Simmonds and Lesley A. Stewart CHAPTER 13 Network Meta-Analysis 238 Georgia Salanti and Julian P.T. Higgins CHAPTER 14 Dose-Response Meta-Analysis 258 Nicola Orsini, Susanna C. Larsson, and Georgia Salanti PART III Specific Study Designs 271 CHAPTER 15 Systematic Reviews of Nonrandomized Studies of Interventions 273 Jelena Savovic, Penny F. Whiting, and Olaf M. Dekkers CHAPTER 16 Systematic Reviews of Diagnostic Accuracy 296 Yemisi Takwoingi and Jonathan J. Deeks CHAPTER 17 Systematic Reviews of Prognostic Factor Studies 324 Richard D. Riley, Karel G.M. Moons, Douglas G. Altman, Gary S. Collins, and Thomas P.A. Debray CHAPTER 18 Systematic Reviews of Prediction Models 347 Gary S. Collins, Karel G.M. Moons, Thomas P.A. Debray, Douglas G. Altman, and Richard D. Riley CHAPTER 19 Systematic Reviews of Epidemiological Studies of Etiology and Prevalence 377 Matthias Egger, Diana Buitrago-Garcia, and George Davey Smith CHAPTER 20 Meta-Analysis in Genetic Association Studies 396 Gibran Hemani PART IV Cochrane and Guideline Development 413 CHAPTER 21 Cochrane: Trusted Evidence. Informed Decisions. Better Health 415 Gerd Antes, David Tovey, and Nancy Owens CHAPTER 22 Using Systematic Reviews in Guideline Development: The GRADE Approach 424 Holger J. Schünemann PART V Outlook 449 CHAPTER 23 Innovations in Systematic Review Production 451 Julian Elliott and Tari Turner CHAPTER 24 Future for Systematic Reviews and Meta-Analysis 463 Shah Ebrahim and Mark D. Huffman PART VI Software 481 CHAPTER 25 Meta-Analysis in Stata 483 David J. Fisher, Marcel Zwahlen, Matthias Egger, and Julian P.T. Higgins CHAPTER 26 Meta-Analysis in R 510 Guido Schwarzer CHAPTER 27 Comprehensive Meta-Analysis Software 535 Michael Borenstein Index 549
Matthias Egger is Professor of Epidemiology and Public Health at the Institute for Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland and the Centre for Infectious Diseases Epidemiology and Research, University of Cape Town, South Africa. Julian P.T. Higgins is Professor of Evidence Synthesis at Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. George Davey Smith is Professor of Clinical Epidemiology and Director of the MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
