Sex, Gender, and Epigenetics: From Molecule to Bedside

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Marianne J. Legato (Professor Emerita of Clinical Medicine, Columbia University, New York, NY, USA)

Sex, Gender, and Epigenetics

From Molecule to Bedside

Marianne J. Legato (Professor Emerita of Clinical Medicine, Columbia University, New York, NY, USA)

$331.95

Paperback

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English

Academic Press Inc
24 May 2023

DNA & Genome

Sex, Gender, and Epigenetics: From Molecule to Bedside explores the complex interplay of sex and gender-based influences on gene expression via epigenetic mechanisms. The book provides an overview of the field and evidence gathered to-date that is followed by a discussion of epigenetic pathways by which biological sex and the impact of the environment collaborate to regulate genetic function. The book also analyzes the impact of ancestors' environmental experience on subsequent generations and describes the nature of sex-specific transmission of environmentally induced epigenetic modifications.

Here, international leaders in the field discuss both sex-specific normal physiology and the experience of disease, with chapters dedicated to fetal programming, microbiome, cancer, bipolar disorder and schizophrenia, embryogenesis, and oocyte aging, among other topics.

Edited by: Marianne J. Legato (Professor Emerita of Clinical Medicine Columbia University New York NY USA)
Imprint: Academic Press Inc
Country of Publication: United States
Dimensions: Height: 235mm, Width: 191mm,
ISBN: 9780128239377
ISBN 10: 0128239379
Pages: 408
Publication Date: 24 May 2023
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

1. Introduction 2. Fetal programming 3. Pharmacology 4. Gender- and Sex Conscious Medicine with Epigenetics in Mind 5. Cancer and Epigenetics 6. Personal Medicine 7. Male Reproduction Epigenetics 8. ART Epigenetics 9. Epigenetics and the Microbiome 10. Stress 11. Sex differences in Gene Regulation in the Brain 12. Epigenetics and the Development of Sex Differences in the Brain 13. Integrative Transcriptomes Reveals Sexually Dimorphic Control of the Cholinergic/Neurokine Interface in Schizophrenia and Bipolar Disorder 14. Transgenerational Epigenetic Inheritance Of Cancer Susceptibility Through The Paternal Germ Line 15. Epigenetic Adaptation Of Ovarian Cancer 16. Cancer epigenetics: Assembly And Function Of Nuclear Domains 17. The epigenetic consequences of infertility and assisted reproduction technology in humans 18. Epigenetic Aspects of Human Oocyte Aging 19. Limited Epigenetic Variation Following Conception Via ART 20. Epigenetic Competence Of Mammalian Gametes And Its Effect On Embryogenesis 21. Heritable Memories 22. Epigenetic Inheritance Of Acquired Traits Through Sperm RNA's And RNA Modifications 23. Mother-Child Transmission Of Epigenetic Information By Tunable Polymorphic Imprinting 24. Stable Phenotype Inheritance From Parents Of Genetic Sequence Per Se 25. Individual Differences; Gene-Environment Interplay and Epigenetics 26. Conclusion and Future Research

Dr. Marianne Legato, Professor Emerita of Clinical Medicine at Columbia University is an internationally known academic physician, author, lecturer, and specialist in gender-specific medicine. She is founding member of the International Society for Gender Medicine and also the founder and director of The Partnership for Gender-Specific Medicine at Columbia University and its next iteration, The Foundation for Gender-Specific Medicine. She has published extensively on gender and sex specific medicine, both scientifically and for the lay public. She is also the founding editor of the journal Gender Medicine, and the journal Gender and the Genome, published for the scientific community. In 1992, Dr. Legato won the American Heart Association's Blakeslee Award for the best book written for the lay public on cardiovascular disease. She is a practicing internist in New York City and has been listed each year in New York Magazine's Best Doctors since the feature's inception in 1993.

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Sex, Gender, and Epigenetics

From Molecule to Bedside

Marianne J. Legato (Professor Emerita of Clinical Medicine, Columbia University, New York, NY, USA)

$331.95

Paperback

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