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Preparation of Radiopharmaceuticals and Their Use in Drug Development by Svend Borup Jensen at Abbey's Bookshop,
Preparation of Radiopharmaceuticals and Their Use in Drug Development
— —
Svend Borup Jensen

Preparation of Radiopharmaceuticals and Their Use in Drug Development

Svend Borup Jensen

$156.95   $125.92

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English
Mdpi AG
19 January 2024
Inorganic chemistry
The purpose of this Special Issue is to bring together research and review papers that use radiopharmaceuticals in drug development. Labeling a potential drug with a radionuclide for imaging and injecting radiopharmaceuticals into animals or humans can immediately provide information about the in vivo destiny of the compound through the application of PET or SPECT scanners. Radionuclides can be useful throughout the whole process of developing new drugs; in particular, if the results obtained are negative and the potential drug can be discarded early on in the process, considerable effort and money can be saved. An alternative way to obtain information about the in vivo destiny/effect of a potential drug is to imagine, for example, a target organ or a tumor with radiopharmaceuticals before and after treatment with a drug. Determining how a drug is metabolized is an integrated part of drug development. Labeling a drug with a radionuclide and providing it with a radioactive tag can help in subsequently determining its location and quantifying metabolites. If the metabolites can be extracted, the solutions can be examined through analytical measurements. Using ionizing radiation in the treatment of tumors is also an application for radiopharmaceuticals which is expected to expand greatly in the years to come. By labeling a specific compound with a radionuclide used for diagnostics we can establish whether it accumulates in the tumor. The same compound is thereafter combined with a radionuclide for treatment.

This Special Issue contains seven original research papers, one communication, and two reviews.
Guest editor:  
Imprint:   Mdpi AG
Dimensions:   Height: 244mm,  Width: 170mm,  Spine: 19mm
Weight:   699g
ISBN:   9783039286270
ISBN 10:   3039286277
Pages:   232
Publication Date:  
Audience:   General/trade ,  ELT Advanced
Format:   Hardback
Publisher's Status:   Active

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