Immunoinformatics: Bioinformatic Strategies for Better Understanding of Immune Function

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Gregory R. Bock Jamie A. Goode

Immunoinformatics

Bioinformatic Strategies for Better Understanding of Immune Function

Gregory R. Bock, Jamie A. Goode

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English

John Wiley & Sons Inc
21 October 2003

Clinical & internal medicine; Biology, life sciences; Biochemical immunology; Biotechnology

Series: Novartis Foundation Symposia

The astounding diversity of the immune system and the complexity of its regulatory pathways makes immunology a combinatorial science. Computational analysis has therefore become an essential element of immunology research and this has led to the creation of the emerging field of immunoinformatics. This book is the first to feature thorough coverage of this new field. Immunoinformatics facilitates the understanding of immune function by modelling the interactions among immunological components. Biological research provides ever deeper insights into the complexity of living organisms while computer science provides an effective means to store and analyse large volumes of complex data. Combining the two fields increases the efficiency of biological research and offers the potential for major advances in the study of biological systems.

This book encompasses key developments in immunoinformatics, including immunological databases, sequence analysis, structure modelling, mathematical modelling of the immune system, simulation of laboratory experiments, statistical support for immunological experimentation and immunogenomics.

The difficulties in effective application of bioinformatic tools in immunology arise at both ends of the spectrum: most immunologists have only a limited comprehension of sophisticated data analysis and applicability and limitations, while the average computer scientist lacks knowledge of the depth and complexity of biological data. The purpose of this book, therefore, is to present contributions from a multidisciplinary team of biologists and computer scientists to explore the issues related to better understanding of immune function and, in particular, to help apply new computer science methods to immunological research.

Related Novartis Foundation symposia:

247 In Silico Simulation of Biological Processes Chair: Denis Noble

252 Generation and effector functions of regulatory lymphocytes Chair: Jean-François Bach

Edited by: Gregory R. Bock, Jamie A. Goode
Imprint: John Wiley & Sons Inc
Country of Publication: United States
Volume: No. 254
Dimensions: Height: 242mm, Width: 160mm, Spine: 17mm
Weight: 567g
ISBN: 9780470853566
ISBN 10: 0470853565
Series: Novartis Foundation Symposia
Pages: 272
Publication Date: 21 October 2003
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.