Following the familiar, easy-to-use at a Glance format and in full-colour, Pathology at a Glance is an accessible introduction and revision text for medical students. Reflecting changes to the curriculum content and assessment methods employed by medical schools, this new edition provides a user-friendly overview of pathology to encapsulate all that the student needs to know.
Pathology at a Glance, Second Edition:
Addresses the key principles of pathology that are central to medicine Contains full-colour artwork throughout, making the subject easy to understand Presents schematic diagrams on the left page and concise explanations on the right Is divided into three sections, covering general and systematic pathology and clinical case examples Contains self-assessment material, including 10 structured case study questions Covers general pathology mechanisms and the clinical pathology of body systems Provides key information on the epidemiology, pathogenesis and clinical features of the major diseases Revision of many chapters, particularly gynaecological pathology, acute cardiac syndromes, paediatric tumours and haematopathology
This book is an invaluable resource for all medical students, of equal benefit for those starting their study of pathology or approaching finals; for junior doctors approaching their membership exams and anybody who needs a handy reference.
Preface 8 Abbreviations 9 Introduction 1 The normal human cell 14 2 Fluid dynamics 18 Tissue damage 3 Tissue types and the effect of tissue damage 22 4 Cell death 26 5 Harmful agents in the environment 28 6 The effects of tobacco, alcohol and other drugs 32 7 Nutritional disorders 36 Inflammation and immunity 8 The body’s natural defences 40 9 B cells and immunoglobulins 44 10 T cells and the TCR 46 11 The major histocompatibility complex 50 12 Primary and secondary lymphoid organs and the monocyte–macrophage (reticuloendothelial) system 52 13 Acute inflammation 56 14 Chronic inflammation 60 15 Wound healing and repair 62 16 Infection and immunodeficiency 64 17 Shock 68 18 Tolerance and autoimmune disease 72 19 Hypersensitivity reactions 76 20 Overview of inflammation and immunity 80 Genetics 21 Cell division 84 22 Genetic disease 86 Neoplasia 23 Disordered cell growth 92 24 Basic concepts in neoplasia 96 25 Tumorigenesis and oncogenesis 100 26 Oncogenes and tumour suppressor genes 102 27 Common carcinoma histological subtypes 106 28 Tumour prognosis and treatment 108 Methods in histocytopathology 29 Basic techniques in histopathology 112 30 Cytopathology 116 31 Molecular pathology 118 Multisystems disease 32 Sarcoidosis and syphilis 122 33 Wilson’s disease and haemochromatosis 124 34 Systemic vasculitis 126 Cardiovascular disease 35 Normal blood vessels and types of aneurysm 130 36 Congenital heart disease 134 37 Systemic hypertension 136 38 Atherosclerosis 138 39 Coronary heart disease 142 40 Thrombosis 146 41 Embolism and disseminated intravascular coagulation 150 42 Cardiac valvular disease 154 43 Myocardial and pericardial disease 156 Respiratory disease 44 Pulmonary vascular disorders 160 45 Pneumonia 162 46 Bronchiectasis 164 47 Tuberculosis 166 48 Chronic obstructive pulmonary disease 170 49 Fibrosing alveolitis 172 50 Primary lung carcinoma 174 51 Other tumours of the lung and pleura 176 Gastrointestinal tract disease 52 Malabsorption 180 53 Peptic ulceration and Helicobacter pylori 184 54 Oesophageal disease 188 55 Tumours of the stomach and small intestine 192 56 Mechanical disease of the gastrointestinal tract 196 57 Inflammatory bowel disease: ulcerative colitis and Crohn’s disease 198 58 Colorectal polyps, colorectal cancer and anal carcinoma 202 Hepatic and pancreaticobiliary disease 59 Normal liver and the effects of liver damage 208 60 Jaundice, gallstones and carcinoma of the gallbladder 210 61 Fatty liver disease: alcoholic and non-alcoholic 212 62 Autoimmune liver disease: AIH, PBC, PSC 216 63 Viral hepatitis 220 64 Cirrhosis 224 65 Acute and chronic pancreatitis 228 66 Tumours of the liver, biliary tree and pancreas 232 Genitourinary tract disease 67 Congenital and inherited abnormalities of the kidney and urinary tract 236 68 The nephron and renal aspects of hypertension 240 69 Glomerulonephritis 242 70 Important types of glomerulonephritis 244 71 Tubulointerstitial diseases 248 72 Renal neoplasms 252 73 Bladder tumours 254 74 Testicular cancer 256 75 Prostatic disease 258 Gynaecological and obstetric disease 76 Vulval and vaginal pathology 262 77 Cervical cancer 266 78 Benign uterine conditions 270 79 Uterine malignancies 272 80 Ovarian neoplasia: part one 274 81 Ovarian neoplasia: part two 278 82 Obstetric pathology 280 83 Paediatric tumours 284 Nervous system disease 84 Cerebrovascular accidents 288 85 Cerebrovascular accident syndromes 290 86 Raised intracranial pressure 292 87 Traumatic injury and intracranial haemorrhage 294 88 Central nervous system tumours 296 89 Infections of the nervous system 298 90 Movement disorders 300 91 Acquired disorders of myelination 304 92 Dementia 306 Endocrine disease 93 Pituitary pathology 310 94 Non-neoplastic pathology of the thyroid 312 95 Thyroid neoplasms 314 96 Parathyroid gland pathology 316 97 Adrenal pathology 318 98 Diabetes mellitus 320 Head and neck pathology 99 Head and neck pathology 324 Lymphoreticular disease 100 Assorted haematological conditions 328 101 Leukaemia 330 102 Lymphoma 332 103 Myeloma 336 104 Myeloproliferative disorders 338 Musculoskeletal disease 105 Muscle disorders 342 106 Arthritis 344 107 Miscellaneous non-neoplastic osteoarticular pathology 348 108 Bone tumours 352 Skin disease 109 Inflammatory dermatoses 356 110 Benign skin tumours 358 111 Malignant skin tumours 360 Breast disease 112 Benign breast disease 364 113 Breast carcinoma 366 Case studies and questions 368 Answers 373 Glossary 378 Reference ranges 380 Index 381
Barry Newell, consultant histopathologist, St George’s Hospital, London Asma Z. Faruqi, consultant histocytopathologist, Barts Health NHS Trust Caroline Finlayson, erstwhile consultant histopathologist, St George’s Hospital, London
