Human Cytogenetics

Constitutional Analysis: A Practical Approach

Rooney, B. H. Czepulkowski

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English

Oxford University Press
01 February 2011

Medicine; Medical laboratory testing & techniques; Cytology; Medical genetics; Genetics (non-medical); Molecular biology

Series: Practical Approach Series

Human Cytogenetics: Constitutional Analysis covers all basic aspects of human cytogenetic study other than malignancies and abnormalities. They are covered in a separate volume.

Since the publication of the 2nd edition in 1992, there have been major advances in technology and the emphasis of this new edition is on the spectrum of technologies available to conventional and molecular cytogenetics. Perhaps the largest new development has been the transition of fluorescence in situ hybridization to an essential tool for all cytogenetecists and consequently its use in chromosome analysis is covered in detail. Another important new technology to be described in detail is computerised image analysis. The conventional techniques have not been forgotten, with chapters on chromosome staining and banding techniques and meiotic studies. New authors have been brought in to take a fresh look at lymphocyte culture and prenatal diagnosis. As before, there is an introduction to human chromosomes, their analyses, and the application of cytogenetic investigations to clinical practice. There is also an appendix on health and safety concerns in the cytogenetics laboratory.

This book will be invaluable to any scientists using basic cytogenetics and along with its sister volume Human Cytogenetics: Malignancy and Acquired Abnormalities will be an essential purchase for any cytogenetics laboratory. The volumes are available individually or as a set.

Edited by: Rooney
Revised by: B. H. Czepulkowski
Imprint: Oxford University Press
Country of Publication: United Kingdom
Edition: 3rd Revised edition
Volume: 240
Dimensions: Height: 190mm, Width: 246mm, Spine: 17mm
Weight: 701g
ISBN: 9780199638390
ISBN 10: 019963839X
Series: Practical Approach Series
Pages: 304
Publication Date: 01 February 2011
Audience: College/higher education , Professional and scholarly , Postgraduate, Research & Scholarly , A / AS level , Undergraduate
Format: Paperback
Publisher's Status: Active

An introduction to human chromosomes and their analyses Lymphocyte culture The cytogenetics of pregnancy Chromosome staining and banding techniques The application of cytogenetic investigations to clinical practice The application of flurorescence in situ hybridisation to chromosome analysis Meiotic studies in man Microscopy, photography and computerised image analysis systems Safety Appendix

Reviews for Human Cytogenetics: Constitutional Analysis: A Practical Approach

This is the much needed and awaited update of a cytogenetics reference last published in 1992 ... Both volumes of this 3rd rdition are outstanding contributions to the practice of clinical cytogenetics and should be fixtures in every cytogentics laboratory. The editor will be pleased to note (as she mentioned in her preface) that my copies sit prominently on my desk and are severely dog-eared Kent E Opheim, PhD, Children's Hospital and Regional Medical Center