Biomolecular Sensors

Electra Gizeli, Christopher R. Lowe

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Hardback

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English

Taylor & Francis Ltd
16 May 2002

Other branches of medicine; Biomedical engineering; Molecular biology; Biosensors

The development of devices that incorporate biological assemblies is impacting analytical and biomedical research. Today, scientists can monitor vital biological interactions-such as the binding of DNA to proteins-in real time,

deriving unique information necessary to understanding biochemical pathways and thus aiding the design of drugs to regulate these processes. Biomolecular Sensors describes the development of this new technology covering the fundamental physics through to applications. The principles of biological recognition, immobilization techniques, and transducer technology are described in depth in order to provide the necessary background to readers from various disciplines. Focusing on the study of antigen-antibody, DNA-protein and receptor-ligand binding events, the book covers biological applications

and describes the commercial instruments available to exploit this technology in areas as diverse as biological research, medical applications and environmental monitoring. With contributions from internationally recognized experts, this is the essential reference for advanced undergraduates and postgraduates as well as professionals in this rapidly advancing field.

Edited by: Electra Gizeli, Christopher R. Lowe
Imprint: Taylor & Francis Ltd
Country of Publication: United Kingdom
Dimensions: Height: 254mm, Width: 178mm, Spine: 21mm
Weight: 816g
ISBN: 9780748407910
ISBN 10: 074840791X
Pages: 336
Publication Date: 16 May 2002
Audience: College/higher education , Professional and scholarly , Professional & Vocational , Further / Higher Education , A / AS level
Format: Hardback
Publisher's Status: Active

Principles of Biological Recognition-Antibody Structure and Biological Function. Protein-protein Interactions. DNA Interactions. Immobilization Chemistry of Biological Recognition Molecules. Binding Isotherms and Kinetics of Immobilized Biological Systems. Optical Transducers. Acoustic Transducers. Capacitance-electrical Transducers. Enzymatic Signal-amplification Transduction. Surface Plasmon Resonance. Grating Coupler. Acoustic Immunosensor

Electra Gizeli, Christopher R. Lowe