Understanding the Process of Aging

The Mitochondrial Production of Oxygen Radicals and Cellular Aging, Alberto Boveris, Lidia E. Costa, and Enrique Cadenas Walking a Tightrope: The Balance Between Mitochondrial Generation and Scavenging of Superoxide Anion, David M. Guidot and Joe M. McCord The Biochemistry of Nitric Oxide and Peroxynitrite: Implications for Mitochondrial Function, Rakesh P. Patel, Trudy Cornwell, and Victor M. Darley-Usmar Oxygen-Dependent Regulation of Biological Functions by Nitric Oxide, Kozo Utsumi, Yoshiki Takehara, Yoko Inai, Munehisa Yabuki, Tomoko Kanno, Manabu Nishikawa, Eisuke F. Sato, and Masayasu Inoue Production of Reactive Oxygen Species in Mitochondria and Age-Associated Pathophysiology: A Reality Check, Henry Jay Forman and Angelo Azzi Functional Roles of Ubiquinone, Jeffery R. Schultz and Catherine Freitag Clarke Mitochondrial Generation of Reactive Oxygen Species and Oxidative Damage During Aging: Roles of Coenzyme Q and Tocopherol, Rajindar S. Sohal, Achim Lass, Liang-Jun Yan, and Linda K. Kwong Mitochondria and Aging: The Mouse's Tale, Steve Esworthy Mitochondria and Apoptosis, Bernard M. Babior, Roberta A. Gottlieb, and Christoph Richter Role of Mitochondria in Oxidative Stress Associated with Aging and Apoptosis: Studies in Intact Cells, Juan Sastre, Federico V. Pallardó, José García de la Asunción, Miguel A. Asensi, Juan M. Esteve, and José Viña-Ribes The Role of Iron and Mitochondria in Aging, Patrick B. Walter, Kenneth B. Beckman, and Bruce N. Ames The Mitochondrial-Lysosomal Axis Theory of Cellular Aging, Ulf T. Brunk and Alexei Terman Quantitative Analysis of Mutations of Mitochondrial DNA During Human Aging, Jörg Napiwotzki, Annette Reith, Andreas Becker, Sandra Leist, and Bernhard Kadenbach Oxidative Damage and Fragility of Mitochondrial DNA, Takayuki Ozawa Mitochondria in Cellular Aging and Degeneration, Gino A. Cortopassi and Alice Wong Mitochondrial Alteration in Aging and Inflammation: A Possible Site of A