‘This new series of Pharmaceutical Indexes will be a boon in academia and the pharmaceutical industry, and provide, as well, a significant addition to the therapeutics discovery arsenal. It should also find a wide audience in government, and the business community.’ – K. Barry Sharpless, Nobel Prize Winner in Chemistry, 2001. ‘The most fruitful basis for the discovery of a new drug is to start with an old drug.’ – James W. Black, Nobel Prize Winner in Physiology or Medicine, 1998.