The Neuroscience of Psychedelics

The Pharmacology of What Makes Us Human

Genís Ona, José Carlos Bouso

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Paperback

Forthcoming
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English

Inner Traditions Bear and Company
18 December 2024

Neurology & clinical neurophysiology; Pharmacology; Neurosciences; Mind, Body, Spirit: thought & practice

A detailed look at the neural and biological mechanisms of psychedelic use

• Examines the main pharmacological properties of psychedelic substances, including LSD, DMT, psilocybin, ayahuasca, mescaline, ketamine, ibogaine, salvia, and MDMA

• Explains the physiological mechanisms behind visionary effects, including what is happening in the brain and how each psychedelic is processed by the body

• Shares safe strategies for using psychedelics, including harm-reduction techniques, and looks at where the future of psychedelic therapies is likely to go

With the widespread legalization of marijuana and the increasing use of psychoactives in controlled therapy settings, further research and understanding of psychedelics is now possible. Yet while individual accounts of their use abound, exactly what’s happening to the brain and body when using these substances is still not widely understood.

Longtime pharmacological researcher Genís Ona presents a comprehensive look at the main pharmacological properties of psychedelic substances, including LSD, DMT, psilocybin, ayahuasca, mescaline, ketamine, ibogaine, salvia, tropane alkaloids, and MDMA. Exploring how psychedelics work within the brain, Ona shares results from his extensive research to reveal the physiological mechanisms that allow these molecules to have their visionary effects, explaining what is happening at the receptor level as well as the “cascade” effects that differ from substance to substance. He examines how the body processes each substance, describing how each psychedelic is released, absorbed, distributed, metabolized, and eliminated. He also details possible dangerous interactions between these substances and other drugs as well as their potential toxicity.

Although his main focus is the biological and neurological effects of psychedelics, Ona also explores the mystical and spiritual dimension of psychedelic use, particularly as practiced in Indigenous traditions, showing how they enable access to a profound spiritual territory. He shares safe strategies for using psychedelics and looks at where the future of psychedelic therapies is likely to go, with an emphasis on ensuring that traditional knowledge is respected, honored, and protected.

By: Genís Ona
Foreword by: José Carlos Bouso
Imprint: Inner Traditions Bear and Company
Country of Publication: United States
Edition: 2nd Edition, Revised Edition of Your Brain on Psychedelics
Dimensions: Height: 229mm, Width: 152mm, Spine: 20mm
Weight: 429g
ISBN: 9798888500040
Pages: 264
Publication Date: 18 December 2024
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Forthcoming

Genís Ona, Ph.D., is a psychologist specializing in pharmacology research. An associate professor at the Universitat Rovira i Virgili (URV), he is a member of the Spanish Society of Psychedelic Medicine and of the working group on psychedelics at the Catalan Society of Psychiatry and Mental Health. He has published more than 50 peer-reviewed scientific articles about psychedelic drugs. Currently working as a study coordinator in the psychedelic trials taking place at Sant Joan de Déu Hospital, Barcelona, and in the Medical Anthropology Research Center at URV, he lives in a house in the middle of the wooded Catalan mountains.