This authoritative, timely, and comprehensively referenced compendium on the bacteriophages explores current views of how viruses infect bacteria. In combination with classical phage molecular genetics, new structural, genomic, and single-molecule technologies have rendered an explosion in our knowledge of phages. Bacteriophages, the most abundant and genetically diverse type of organism in the biosphere, were discovered at the beginning of the 20th century and enjoyed decades of used as anti-bacterial agents before being eclipsed by the antibiotic era. Since 1988, phages have come back into the spotlight as major factors in pathogenesis, bacterial evolution, and ecology. This book reveals their compelling elegence of function and their almost inconceivable diversity.
Much of the founding work in molecular biology and structural biology was done on bacteriophages. These are widely used in molecular biology research and in biotechnology, as probes and markers, and in the popular method of assesing gene expression.
Ry Young: Foreword Contributors PART I: General Background of Phage Biology 1: William C. Summers: Phage and the Early Development of Molecular Biology 2: Hans-W. Ackermann: Classification of Bacteriophages 3: Harald Bruüssow: Prophage Genomics 4: Harald Bruüssow and Frank Desiere: Evolution of Tailed Phages: Insights from Comparative Phage Genomics 5: Stephen T. Abedon: Phage Ecology PART II: Life of Phages 6: Paul J. Jardine and Dwight L. Anderson: DNA Packaging in Double-Stranded DNA Phages 7: Allan Campbell: General Aspects of Lysogeny 8: John W. Little: Gene Regulatory Circuitry of Phage l 9 Regulation of l Gene Expression by Transcription Termination and Antitermination: David I. Friedman and Donald L. Court: 10: Ry Young and Ing-Nang Wang: Phage Lysis PART III: Cubic and Filamentous Phages 11: Bentley A. Fane, Karie L. Brentlinger, April D. Burch, Min Chen, SusanHafenstein, Erica Moore, Christopher R. Novak, and Asako Uchiyama: qX174 et al., the Microviridae 12: Marjorie Russel and Peter Model: Filamentous Phage 13: A. Marika Grahn, Sarah J. Butcher, Jaana K. H. Bamford, and Dennis H. Bamford: PRD1: Dissecting the Genome, Structure, and Entry 14: Dennis H. Bamford and Jaana K. H. Bamford: Lipid-Containing Bacteriophage PM2, the Type Organism of Corticoviridae 15: Jan van Duin and Nina Tsareva: Single-Stranded RNA Phages 16: Leonard Mindich: Phages with Segmented Double-Stranded RNA Genomes PART IV: Individual Tailed Phages 17: Gregory J. German, Rajeev Misra, and Andrew M. Kropinski: The T1-Like Bacteriophages 18: Gisela Mosig and Fred Eiserling: T4 and Related Phages: Structure and Development 19: Jon R. Sayers: Bacteriophage T5 20: Ian J. Molineux: The T7 Group 21: Krystyna M. Kazmierczak and Lucia B. Rothman-Denes: Bacteriophage N4 22: Margarita Salas: Phage q29 and its Relatives 23: Juan C. Alonso, Paulo Tavares, Rudi Lurz, and Thomas A. Trautner: Bacteriophage SPP1 24: Hansjörg Lehnherr: Bacteriophage P1 25: Anders S. Nilsson and Elisabeth Haggård Ljungquist: The P2-Like Bacteriophages 26: Gianni Dehò and Daniela Ghisotti: The Satellite Phage P4 27: Roger W. Hendrix and Sherwood Casjens: Bacteriophage l and its Genetic Neighborhood 28: Nikolai V. Ravin: N15: The Linear Plasmid Prophage 29: Peter E. Prevelige, Jr.: Bacteriophage P22 30: Luciano Paolozzi and Patrizia Ghelardini: The Bacteriophage Mu PART V: Phages by Host or Habitat 31: Kenneth M. Stedman, David Prangishvili, and Wolfram Zillig: Viruses of Archaea 32: Nicholas H. Mann: Phages of Cyanobacteria 33: Robert V. Miller: Marine Phages 34: Stefan Hertwig, Mikael Skurnik, and Bernd Appel: Yersinia Phages 35: Pamela S. Fink and Stanley A. Zahler: Temperate Bacteriophages of Bacillus subtilis 36: Lone Brønsted and Karin Hammer: Phages of Lactococcus lactis 37: Martin J. Loessner and Richard Calendar: The Listeria Bacteriophages 38: Graham F. Hatfull: Mycobacteriophages 39: Margaret C. M. Smith: Molecular Genetics of Streptomyces Phages 40: Jack Maniloff and Kevin Dybvig: Mycoplasma Phages 41: Harald Brüssow and Juan E. Suárez: Lactobacillus Phages PART VI: Applications 42: Gregg Bogosian: Control of Bacteriophage in Commercial Microbiology and Fermentation Facilities 43: Noreen E. Murray: Phage-Based Expression Systems 44: Bjorn H. Lindqvist: Phage in Display 45: Charles P. Gerba: Bacteriophage as Pollution Indicators 46: Cath Rees: The Use of Phage as Diagnostic Systems 47: Patrick L. Wagner and Matthew K. Waldor: Bacteriophages in Bacterial Pathogenesis 48: Carl R. Merril, Dean Scholl, and Sankar Adhya: Phage Therapy Index
Richard Calendar is Professor of Molecular and Cell Biology at the University of California at Berkeley. He has been studying bacteriophages since 1966.
Reviews for The Bacteriophages
<br> In summary, the book is a well-edited, comprehensive survey of phage researches and could be recommended for scientists working in various areas of biology. Immunological Investigations<br>
