The Age of Genomes

Tales from the Front Lines of Genetic Medicine

Steven Monroe Lipkin, Jon Luoma

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English

Beacon Press
01 September 2018

Maturation & ageing; Medical genetics

A leading geneticist explores what promises to be one of the most transformative advances in health and medicine in history

Almost every week, another exciting headline appears about new advances in the field of genetics. Genetic testing is experiencing the kind of exponential growth once seen with the birth of the Internet, while the plummeting cost of DNA sequencing makes it increasingly accessible for individuals and families.

Steven Lipkin and Jon Luoma posit that today's genomics is like the last century's nuclear physics- a powerful tool for good if used correctly, but potentially dangerous nonetheless. DNA testing is likely the most exciting advance in a long time for treating serious disease, but sequencing errors, complex biology, and problems properly interpreting genetic data can also cause life-threatening misdiagnoses of patients with debilitating and fatal genetic diseases. DNA testing can also lead to unnecessary procedures and significantly higher health-care costs. And just around the corner is the ability to cure genetic diseases using powerful gene-editing technologies that are already being used in human embryo research. Welcome to the Age of Genomes!

The Age of Genomes immerses readers in true stories of patients on the frontier of genomic medicine and explores both the transformative potential and risks of genetic technology. It will inform anxious parents increasingly bombarded by offers of costly new prenatal testing products, and demonstrate how genetic technology, when deployed properly, can significantly improve the lives of patients who have devastating neurological diseases, cancer, and other maladies. Dr. Lipkin explains the science in depth, but in terms a layperson can follow.

By: Steven Monroe Lipkin, Jon Luoma
Imprint: Beacon Press
Country of Publication: United States
Dimensions: Height: 236mm, Width: 157mm, Spine: 23mm
Weight: 490g
ISBN: 9780807074572
ISBN 10: 0807074578
Pages: 256
Publication Date: 01 September 2018
Audience: General/trade , ELT Advanced
Format: Hardback
Publisher's Status: Active

Introduction ONE The Parisian Housekeeper TWO The Unactionables THREE Altitude Sickness FOUR The Blindfolded Poker Player and the Smoked Salmon FIVE The Evil Twin SIX Madonna and Putto, Mortar and Plaster SEVEN The DIY Genome EIGHT Generation XX/XY NINE The Tilted Driver’s Test TEN Fingerprints, Written in Blood ELEVEN The Decorated Genome TWELVE The Age of Geneticism Notes Index

Steven Monroe Lipkin, MD, PhD, FACMG, has been a practicing clinical geneticist for almost twenty years. He directs the Adult and Cancer Genetics Clinic and is the vice chair for Translational Research at the Sanford I. and Joan Weill Department of Medicine at Weill Cornell in New York City. Jon R. Luoma's writing about science and the environment has appeared in National Geographic, GQ, the New York Times Sunday Magazine, and Audubon, where he was a longtime contributing editor. He is the author of three previous nonfiction books- The Hidden Forest, A Crowded Ark, and Troubled Skies, Troubled Waters.

Reviews for The Age of Genomes: Tales from the Front Lines of Genetic Medicine

Lipkin s The Age of Genomes is a thrilling and deeply relevant book. Spanning a multitude of topics breast cancer, the genetics of Tay-Sachs disease, and an individual s assessment of his or her own genetic risk Lipkin writes with a deft and humane touch, reminding us how profoundly the new science of genomics will impact all of us in the future. Siddhartha Mukherjee, MD, author of The Emperor of All Maladies and The Gene: An Intimate History If you re thinking about having your genome sequenced, or just learning about genomics, The Age of Genomes is an extraordinary resource. Steven Lipkin, one of the country s leading medical geneticists, teaches us through his patients and insightful stories. Eric Topol, MD, author of The Patient Will See You Now Building on his own experiences as a highly regarded physician, Dr. Lipkin has expertly woven a series of engaging stories to portray the enormous potential, as well as the possible pitfalls, of the new genomic era. Lee Goldman, MD, author of Too Much of a Good Thing: How Four Key Survival Traits Are Now Killing Us