Systems Biology and In-Depth Applications for Unlocking Diseases: Principles, Tools, and Application to...

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Babak Sokouti (Assistant Professor and Head of Systems Medicine, Bioinformatics, and Molecular Modeling Laboratory, Biotechnology Research Center, Tabriz University of Medical Sciences, Iran)

Systems Biology and In-Depth Applications for Unlocking Diseases

Principles, Tools, and Application to Disease

Babak Sokouti (Assistant Professor and Head of Systems Medicine, Bioinformatics, and Molecular Modeling Laboratory, Biotechnology Research Center, Tabriz University of Medical Sciences, Iran)

$318.95

Paperback

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English

Academic Press Inc
08 November 2024

Biomedical engineering

Systems Biology and In-Depth Applications for Unlocking Diseases provides the essence of systems biology approaches in a practical manner illustrating the basic principles essential to develop and model in real life science applications. Methodologies covered show how to interrogate biological data, with the purpose of obtaining insight about disease diagnosis, prognosis, and treatment.

Systematically written in 4 parts, this book first provides an introduction and history of systems biology; second, it provides the tools and resources needed for the structure and function of biological systems; next, it provides the evidence of systems biology in action to better understand disease connections; and finally, it provides the extensions of systems biology in various scientific fields including pharmacology, immunology, vaccinology, neuroscience, virology, and medicine. Examples include big data techniques, scale networks, mathematical model development, and much more.

This is the perfect reference to provide the fundamental base of knowledge needed for systems biologists, professionals in systems medicine, computational biologists, and bioinformaticians, whether needed for immediate application or for building a comprehensive understanding of the field.

Edited by: Babak Sokouti (Assistant Professor and Head of Systems Medicine Bioinformatics and Molecular Modeling Laboratory Biotechnology Research Center Tabriz University of Medical Sciences Iran)
Imprint: Academic Press Inc
Country of Publication: United States
Dimensions: Height: 276mm, Width: 216mm,
Weight: 980g
ISBN: 9780443223266
ISBN 10: 0443223262
Pages: 354
Publication Date: 08 November 2024
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

Part 1. Introduction 1.1 Systems biology at a glance 1.2. A history on systems biology evolution 1.3. Brief information on cellular biology and signaling pathways 1.4. Systems biology: where are we? 1.5. Filling the gaps between systems biology and cell biology 1.6 Concluding remarks 1.7 Mathematical concepts 1.5. Kinetic and dynamics of biological systems Part 2. Tools and Resources 2.1. Biological data sources 2.1.1. Microarray 2.1.2. Next generation sequencing (NGS) 2.1.3. Comparative genomic hybridization (CGH) 2.1.4. Single nucleotide polymorphisms (SNP) 2.2. High throughput data 2.1.2. Databases 2.3. Programming, tools and software Part 3. Systems biology in action – to understand diseases 3.1 Big data analysis techniques 3.2 Reconstruction of genome and proteomic scale network structures and functions 3.3 Validation strategies 3.3.1 Mathematical model development 3.3.2 Biological gene expression models 3.3.3 Experimental techniques 3.4 Applications of systems biology extensions in diseases 3.4.1 Systems immunology 3.4.2 Systems pharmacology 3.4.3 Systems virology 3.4.4 Systems vaccinology 3.4.5 Systems neuroscience 3.4.6 Systems medicine 3.4.7 Future directions on systems biology

Dr. Sokouti is an Assistant Professor and Head of Systems Medicine, Bioinformatics, and Molecular Modeling Laboratory, Biotechnology Research Center, Tabriz University of Medical Sciences. This is his third edited book, and he has authored multiple book chapters and journal articles.

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Systems Biology and In-Depth Applications for Unlocking Diseases

Principles, Tools, and Application to Disease

Babak Sokouti (Assistant Professor and Head of Systems Medicine, Bioinformatics, and Molecular Modeling Laboratory, Biotechnology Research Center, Tabriz University of Medical Sciences, Iran)

$318.95

Paperback

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