Recent progress has led to a better understanding of the molecular structure of sodium channels, how they work and the mechanisms that restrict their expression to particular cell types. This book explains how these channels are modulated in various pathological states to enable the development of therapeutic strategies based on sodium channel restoration.
The authors present the most current research on sodium channels and neuronal function.
Brings together both the basic biology and biophysics with detailed consideration of the medical applications in chronic pain and epilepsy. Includes coverage of channelopathies, sodium channel gene expression, the modulation of sodium channels, and molecular mechanisms of gating and drug block of sodium channels.
Edited by:
Gregory R. Bock, Jamie A. Goode Imprint: John Wiley & Sons Inc Country of Publication: United States Volume: No. 241 Dimensions:
Height: 238mm,
Width: 159mm,
Spine: 17mm
Weight: 538g ISBN:9780471485308 ISBN 10: 0471485306 Series:Novartis Foundation Symposia Pages: 248 Publication Date:21 November 2001 Audience:
College/higher education
,
Professional and scholarly
,
Further / Higher Education
,
Undergraduate
Format:Hardback Publisher's Status: Active
The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.