A complete guide to the diagnosis and management of cutaneous lymphomas and pseudolymphomas
Easily misdiagnosed as benign skin diseases, malignant cutaneous lymphomas can present a variety of challenges to trainees and practicing specialists alike. Skin Lymphoma: The Illustrated Guide has been designed to alleviate some of these difficulties, providing all those working in the dermatological field with a complete and easily consulted text on this potentially fatal cancer. Authored by renowned dermatopathologist Professor Lorenzo Cerroni, its exhaustive contents cover the clinical presentations and pathological correlates of cutaneous lymphomas in their various forms, alongside their prognoses and strategies for treatment.
This expanded fifth edition features a wealth of enhancements and additions, including new chapters, updated content, and more than 1,300 full-color illustrations. Revised to reflect the most recent World Health Organization (WHO) and European Organization for Research and Treatment of Cancer (EORTC) classifications, its cutting-edge approach to its subject incorporates the latest molecular data, alongside more familiar histopathological and clinical features. The book’s considerable scope has been broadened into new and groundbreaking areas, the details of which are explored in chapters discussing primary cutaneous acral CD8+ T-cell lymphoma, composite lymphomas, and non-neoplastic cutaneous signs of systemic lymphomas, as well as in new sections on previously unexamined entities such as implant–associated anaplastic large cell lymphoma.
Fully updated with new genetic data and most recent WHO classifications Contains four newly written chapters Features unconventional presentation sections with commentary on diagnosis Includes more than 1,300 color illustrations
Skin Lymphoma: The Illustrated Guide is an indispensable resource forclinical dermatologists, dermatopathologists, and any other medical practitioners and trainees involved in the diagnosis and treatment of skin lymphomas.
By:
Lorenzo Cerroni (Medical University of Graz Austria)
Imprint: Wiley-Blackwell
Country of Publication: United Kingdom
Edition: 5th edition
Dimensions:
Height: 277mm,
Width: 224mm,
Spine: 31mm
Weight: 1.701kg
ISBN: 9781119485902
ISBN 10: 1119485908
Pages: 600
Publication Date: 08 October 2020
Audience:
Professional and scholarly
,
Undergraduate
Replaced By: 9781394235483
Format: Hardback
Publisher's Status: Active
List of Teaching Cases xi Preface xiii Acknowledgments xv 1 Introduction 1 Section 1: Cutaneous NK/T‐Cell lymphomas 2 The ‘‘parapsoriases’’: A Riddle, Wrapped in a Mystery, Inside an Enigma 15 3 Mycosis Fungoides 23 4 Sézary Syndrome 113 5 Primary Cutaneous CD30+ Lymphoproliferative Disorders 133 Lymphomatoid Papulosis 134 Cutaneous Anaplastic Large Cell Lymphoma 150 “Borderline” Cases 167 Intralymphatic CD30+ Large T‐Cell Lymphoma 168 Implant‐Associated Anaplastic Large Cell Lymphoma 170 6 Subcutaneous Panniculitis‐like T‐cell Lymphoma 180 7 Aggressive Cutaneous Cytotoxic Lymphomas 195 Primary Cutaneous Aggressive Epidermotropic CD8+ Cytotoxic T‐Cell Lymphoma 196 Primary Cutaneous γ/δ T‐Cell Lymphoma 201 Cutaneous Extranodal NK/T‐Cell Lymphoma, Nasal Type 208 8 Cutaneous Peripheral T‐cell Lymphoma, Not Otherwise Specified (NOS) 219 9 Cutaneous CD4+ Small/Medium T‐cell Lymphoproliferative Disorder 228 10 Acral CD8+ Cutaneous T‐cell Lymphoma 235 11 Cutaneous Adult T‐cell Leukemia/Lymphoma 239 12 Other Cutaneous NK/T‐cell Lymphomas 243 Cutaneous Angioimmunoblastic T‐Cell Lymphoma 243 Hydroa Vacciniforme‐Like Lymphoproliferative Disorder 246 Severe Mosquito Bite Allergy 250 Section 2: Cutaneous B‐Cell lymphomas 13 Cutaneous Follicle Center Lymphoma 255 14 Cutaneous Marginal Zone Lymphoma (Cutaneous MALT Lymphoma) and Variants 274 Cutaneous Marginal Zone Lymphoma, Conventional Variant 276 Cutaneous Marginal Zone Lymphoma, Lymphoplasmacytic Variant 287 Cutaneous Marginal Zone Lymphoma, Plasmacytic Variant 290 Cutaneous Marginal Zone Lymphoma, Blastoid Variant 292 Cutaneous Amyloidoma 293 15 Cutaneous Diffuse Large B‐cell Lymphoma, Leg Type 299 16 Intravascular Large Cell Lymphomas 315 Intravascular Large B‐Cell Lymphoma 316 Intravascular Large NK/T‐Cell Lymphoma 321 17 Other Cutaneous B‐cell Lymphomas 326 Epstein–Barr Virus (EBV)‐Positive Cutaneous Diffuse Large B‐Cell Lymphoma, Not Otherwise Specified (NOS) 326 Specific Cutaneous Manifestations in Mantle Cell Lymphoma 329 Specific Cutaneous Manifestations in Extracavitary Primary Effusion Lymphoma 331 Specific Cutaneous Manifestations in Multiple Myeloma 334 Specific Cutaneous Manifestations in Burkitt Lymphoma 336 Cutaneous Lymphomatoid Granulomatosis 340 Cutaneous Plasmablastic Lymphoma 342 Cutaneous T‐Cell/Histiocyte‐Rich Large B‐Cell Lymphoma 344 Cutaneous Manifestations in Waldenstrom Macroglobulinemia 346 Epstein–Barr Virus (EBV)‐Associated Mucocutaneous Ulcers 347 Section 3: Cutaneous lymphomas in immunosuppressed individuals 18 Cutaneous Lymphomas in Immunosuppressed Individuals 357 Cutaneous Posttransplant Lymphoproliferative Disorders 358 Cutaneous Lymphomas in HIV‐Infected Individuals 365 Cutaneous Lymphoproliferative Disorders in Other Iatrogenic and Non‐Iatrogenic Immune Deficiencies 368 Section 4: Specific cutaneous manifestations of leukemias and of precursor hematologic neoplasms 19 Cutaneous Manifestations of B‐cell Chronic Lymphocytic Leukemia 379 Progression to Diffuse Large B‐Cell Lymphoma (Richter Syndrome) 385 20 Cutaneous Manifestations of Myelogenous Leukemia 390 Chronic Myeloid Leukemia 399 Myelodysplastic Syndromes 400 21 Blastic Plasmacytoid Dendritic Cell Neoplasm 407 Mature Plasmacytoid Dendritic Cell Proliferations Associated With Myeloid Neoplasms 415 22 Cutaneous Manifestations of Other Leukemias 419 T‐Cell Prolymphocytic Leukemia 419 Aggressive Natural Killer Cell Leukemia 421 Specific Skin Manifestations of Other Types of Leukemia 422 23 Cutaneous Lymphoblastic Lymphomas 424 Cutaneous B‐Lymphoblastic Lymphoma 424 Cutaneous T‐Lymphoblastic Lymphoma 428 Section 5: Cutaneous manifestations of other lymphomas and non‐neoplastic cutaneous signs of systemic lymphomas 24 Cutaneous Manifestations of Hodgkin Lymphoma 437 Primary Cutaneous Hodgkin Lymphoma 440 25 Cutaneous Composite Lymphomas 443 26 Nonneoplastic Cutaneous Signs of Systemic Lymphomas 450 Section 6: Cutaneous lymphomas in children and adolescents 27 Cutaneous Lymphomas in Children and Adolescents 463 Mycosis Fungoides 463 Sézary Syndrome 464 Lymphomatoid Papulosis 467 Cutaneous Anaplastic Large Cell Lymphoma 467 Subcutaneous Panniculitis‐Like T‐Cell Lymphoma 468 Primary Cutaneous Aggressive Epidermotropic CD8+ Cytotoxic T‐Cell Lymphoma 468 Primary Cutaneous γ/δ T‐Cell Lymphoma 468 Extranodal NK/T‐Cell Lymphoma, Nasal Type 468 Primary Cutaneous Peripheral T‐Cell Lymphoma, not Otherwise Specified (NOS) 468 Cutaneous CD4+ Small/Medium T‐Cell Lymphoproliferative Disorder 468 Cutaneous Angioimmunoblastic T‐Cell Lymphoma 468 Epstein–Barr Virus (EBV)‐Positive T‐Cell and NK‐Cell Lymphoproliferative Diseases of Childhood (Hydroa Vacciniforme‐Like Lymphoproliferative Disorder, Severe Mosquito Bite Allergy) 468 Adult T‐Cell Lymphoma/Leukemia 469 Acral CD8+ T‐Cell Lymphoma 469 Cutaneous Follicle Center Lymphoma 469 Cutaneous Marginal Zone Lymphoma (Cutaneous MALT Lymphoma) 469 Cutaneous Burkitt Lymphoma 469 Cutaneous Intravascular Large Cell Lymphoma 469 Cutaneous Lymphomatoid Granulomatosis 469 EBV+ Mucocutaneous Ulcer 469 Cutaneous Lymphomas in Immunosuppressed Children and Adolescents 469 Cutaneous Manifestations of Myelogenous Leukemia 469 Blastic Plasmacytoid Dendritic Cell Neoplasm 470 Cutaneous Lymphoblastic Lymphoma (B or T Cell) 470 Section 7: Pseudolymphomas of the skin 28 Pseudolymphomas of the Skin 475 Chronic Actinic Dermatitis (Actinic Reticuloid) 477 Lymphomatoid Contact Dermatitis 478 Non‐mycosis Fungoides‐associated Follicular Mucinosis and Other Mimickers of Pilotropic Mycosis Fungoides 479 Solitary Idiopathic B/T‐cell Pseudolymphoma 481 Lichenoid (Lymphomatoid) Keratosis 483 T‐cell‐Rich Angiomatoid Polypoid Pseudolymphoma/ Acral Pseudolymphomatous Angiokeratoma in Children/ Pretibial Lymphoplasmacytic Plaque in Children (“T/B‐cell Angiomatoid Pseudolymphoma”) 486 Lichen Aureus/Lichenoid Pigmented Purpuric Dermatitis 487 Lichen Sclerosus 489 Vitiligo 489 Annular Lichenoid Dermatitis of Youth 490 Pseudolymphomatous Acrodermatitis Chronica Atrophicans 493 Pseudolymphomatous Atopic Dermatitis 495 Nonneoplastic Erythroderma in Adult Patients 496 Pseudolymphomatous Cutaneous Infiltrates in Human Immunodeficiency Virus (HIV)‐Infected Patients and in Other Immune Deficiencies 499 CD30+ T‐cell Pseudolymphomas 502 Persistent Nodular Arthropod Bite Reactions and Nodular Scabies 502 Pseudolymphomas in Herpes Simplex and Herpes Zoster Infections 504 Hydroa Vacciniforme 506 Pityriasis Lichenoides 507 Pseudolymphomas Associated with Lupus Erythematosus 511 Lymphomatoid Drug Reactions 515 Lymphocytoma Cutis 516 Lymphocytoma Cutis Associated with Borrelia Infection 518 Pseudolymphomas at Sites of Vaccination 522 Pseudolymphomas in Tattoos 524 Localized Scleroderma/Morphea 524 Cutaneous IgG4‐Related Disease 526 Pseudolymphomas in Syphilis 529 Cutaneous Plasma Cell Granuloma 534 Cutaneous and Systemic Plasmacytosis 535 Cutaneous Manifestations of Castleman Disease 536 Cutaneous Extramedullary Hematopoiesis 537 Histiocytoid Sweet Syndrome 538 Intralymphatic Histiocytosis 539 Benign Intralymphatic Proliferation of T‐cell Lymphoid Blasts 541 Other “Accidental” Pseudolymphomas 543 “Malignant” Pseudolymphomas 546 Section 8: The cutaneous “atypical lymphoid proliferation” 29 The Cutaneous “Atypical Lymphoid Proliferation” 565 Index 569
LORENZO CERRONI, MD, is Professor of Dermatology and Venereology and Director of the Dermatopathology Research Center at the Medical University of Graz, Graz, Austria.
