Silkworm Biofactory: Silk to Biology

— —

Katsumi Maenaka (Hokkaido University, Japan) Enoch Y. Park (Research Institute of Green Science & Technology, Japan)

Silkworm Biofactory

Silk to Biology

Katsumi Maenaka (Hokkaido University, Japan), Enoch Y. Park (Research Institute of Green Science & Technology, Japan)

$96.99

Paperback

Not in-store but you can order this
How long will it take?

Availability Information

We source books from suppliers in Australia and overseas. For books we don't currently have in stock, the time it takes to get them from our suppliers can vary widely - from a few days to a few months - so we check each book with each supplier to determine the expected time it will take to be supplied to us.

We then advise you accordingly. If the time taken to get any book is too long for you, you can let us know and we will cancel or adjust your order, and refund as required.

To find out the anticipated arrival time for specific items prior to ordering, please contact us by phone or email:

Phone +61 2 9264 3111, or 1800 4 BOOKS (1800 4 26657) if outside Sydney:
option 1 Abbey's Bookshop (Crime, History, Science, Kids & more) • info@abbeys.com.au
option 2 Language Book Centre (ESL & Foreign Languages) • language@abbeys.com.au
option 3 Galaxy Bookshop (Sci-fi, Fantasy, Romance, Graphic Novels) • sf@galaxybooks.com.au

QTY:

English

CRC Press
31 March 2021

Zoology: Invertebrates; Pharmaceutical technology

Series: Industrial Biotechnology

While silk derived from silkworm has been of economic importance for centuries, more recently silkworm has been found to have utility in biomedicine. This has attracted attention for expressing eukaryotic recombinant proteins, which require post-translational modifications. In 1985 Dr. Susumu Maeda demonstrated that silkworm larvae could produce a functional human-interferon. Since then various techniques have been developed to express recombinant proteins in silkworm. With the development of the Bombyx mori nucleopolyhedrovirus (BmNPV) bacmid system, which is capable of replicating in both Escherichia coli and Bombyx mori derived cell lines or silkworm, silkworm larvae or pupae have been used for the expression system for recombinant protein production. This method has the advantage of a bacmid, in that it can be easily prepared for sufficient bacmid DNA for subsequent expression in silkworm. It is potentially a big breakthrough in production of recombinant eukaryotic proteins and viruses, which will be a powerful tool in a new proteome era.

This volume contributes to the advancement of our knowledge in the subject, for example gene expression systems and silkworm research, and focuses on silkworm biofactories for the recombinant protein production and commercial applications of proteins.

Edited by: Katsumi Maenaka (Hokkaido University Japan), Enoch Y. Park (Research Institute of Green Science & Technology, Japan)
Imprint: CRC Press
Country of Publication: United Kingdom
Dimensions: Height: 234mm, Width: 156mm,
Weight: 680g
ISBN: 9780367780722
ISBN 10: 0367780720
Series: Industrial Biotechnology
Pages: 300
Publication Date: 31 March 2021
Audience: College/higher education , General/trade , Primary , ELT Advanced
Format: Paperback
Publisher's Status: Active

Prof. Enoch Y. Park is a professor at Research Institute of Green Science and Technology (RIGST), Shizuoka, Japan. He received a Ph.D. in 1990 from the University of Tokyo. He was assistant professor at Nagoya University, Japan from 1990 and then associate professor at Shizuoka University from 1994 and a professor from 1999. In 2013 he was appointed Director of RIGST, Shizuoka University. He developed a bacmid expression system in silkworm. He has authored/co-authored about 280 original articles, reviews and book chapters, in the field of protein expression, biotechnology, and nanobiotechnology. Prof. Katsumi Maenaka is a professor at Laboratory of Biomolecular Science, and Director, Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University, Japan. He received his Ph.D. in 1996 from the University of Tokyo. He was a HFSP postdoctoral fellow at University of Oxford, assistant professor at National Institute of Genetics, associate professor at Kyushu University and professor at Hokkaido University in 2010. He developed a bacmid expression system in silkworm with Prof. Park. He has published many original articles, reviews and book chapters, in the field of protein engineering, structural biology, immunology, virology and drug discovery.