Information on the changing epidemiology and expanding nosological range of Q fever in humans has gained much attention in the past decade. Q fever is a zoonotic disease caused by the highly infectious pathogen Coxiella burnetii and has global distribution with important health, social and economic implications. A number of other properties and characteristics of the causative agent and disease, define Q fever as a lasting and difficult veterinary and epidemiological problem, namely: the adaptability of C. burnetii and its high resistance in the external environment; the possibility of the existence of the agent in three- and two-member parasitic systems; the availability of natural and agricultural foci of infection; peculiarities of pathogenesis in humans and animals, and the mechanisms of excretion of the pathogen into the environment; and the high susceptibility of non-immune populations of animals and people. Given that C. burnetii is included in the arsenal of bacteriological weapons as agent with potential bioterrorist threat must be borne in mind the strategic importance of this microorganismThis book summarizes and analyzes the scientific facts and developments about Q Fever researched worldwide and performed by the author to propose a system for monitoring, control and prevention covering the main necessary actions, measures and activities in the fight against this fever. There is an uneven level of knowledge of Q fever in animals and humans in various countries on the planet, while the assessment of the relevance of the problem is often ambiguous and unrealistic in terms of veterinary, medical and social and economic aspects, which can result in an incomplete diagnosis, inaccurate information about the spread of disease and lack of purposeful struggle. The scientific topics discussed include: Biological, morphological and immunological properties of Coxiella burnetiiDiagnosis, clinical forms and manifestations, pathologic changesEpidemiology of Q fever in animals and humansPrevention and Control
By:
Svetoslav P. Martinov
Imprint: River Publishers
Country of Publication: Denmark
Dimensions:
Height: 234mm,
Width: 156mm,
Spine: 21mm
Weight: 666g
ISBN: 9788793519497
ISBN 10: 8793519494
Pages: 344
Publication Date: 31 March 2017
Audience:
Professional and scholarly
,
Undergraduate
Format: Hardback
Publisher's Status: Active
Abbreviations; Introduction; 1. Historical Notes; 2. Etiology and taxonomy; 3. Morphological characteristics, development cycle, interaction with cells; 4. Ultrastructure of Coxiella burnetii and electronmicroscopic diagnosis of Q fever; 5. Isolation and culture of Coxiella burnetii; 6. Virulence and pathogenicity; 7. Antigens and phase variability; 8. Serology; 9. Polymerase chain reaction; 10. Clinical picture; 11. Pathogenesis and pathological morphology; 12. Epizootiology and epidemiology; 13. Sensitivity to antibiotics and treatment; 14. Prevention and control; Bibliography
Professor Svetoslav P. Marrtinov, DVM, Ph.D., D.Sci. Director of the Central Research Veterinary Medical Institute - Sofia, Bulgaria (1990-2001). Longtime Head of the National Reference Laboratory of Chlamydia and Rickettsia at the institute. He was Head of the Department of especially dangerous infections and zoonoses and Head of the Department of virology and viral diseases at the National Diagnostic and Research Veterinary Medical Institute - Sofia. He works in the fields of microbiology, virology, infectious diseases in animals, and zoonoses. Publications: more than 300 in these directions. Manages or participates in numerous national and international research projects. Over the years, the activities of Professor Martinov also include his work as first Vice-President of the Union of Veterinarians in Bulgaria, founder and first chairman of the Veterinary Association of the countries from Balkan and Black Sea region, member of the Supreme Veterinary Council at the Ministry of Agriculture in Bulgaria, and Vice-President, Bulgarian Society of Medical Geography. He is a member of several national and international scientific societies. Biographical data about Dr. Martinov are included in several editions of the American Biographical Institute, USA, and the International Biographical Centre, Cambridge, England.
