WIN $150 GIFT VOUCHERS: ALADDIN'S GOLD

Close Notification

Your cart does not contain any items

Patients with Autosomal Dominant Polycystic Kidney Disease by Shewata Pandita at Abbey's Bookshop,
Patients with Autosomal Dominant Polycystic Kidney Disease
— —
Shewata Pandita

Patients with Autosomal Dominant Polycystic Kidney Disease

Shewata Pandita

$57.95   $49.55

Paperback

Not in-store but you can order this
How long will it take?
English
Akhand Publishing House
16 December 2022
Renal medicine & nephrology
Autosomal Dominant Polycystic Kidney Disease (ADPKD) accounts for 2.6% of the

patients with Chronic Kidney Disease in India. The disease is caused by pathogenic

sequence variants in either PKD1 or PKD2 gene. The primary aim of the present

study was to evaluate PKD1 and PKD2 genes to identify the disease causing variants

in patients of ADPKD. A significant phenotypic variability is observed in patients of

ADPKD with respect to progression of the disease. Genetic modifying factors are

reported to be associated with this variability and thus, identification of these factors

could inform about targets for intervention. Given this, an attempt was made to

investigate the role of Glu298Asp (c.894G>T) polymorphism of NOS3 gene and two

promoter polymorphisms (-2578C>A and -1154G>A) of VEGF gene in progression

of disease in ADPKD patients.

PKD1 and PKD2 variants were analyzed by direct gene sequencing and/or multiplex

ligation-dependent probe amplification (MLPA) in 125 unrelated patients of ADPKD.

The pathogenic potential of the variants was evaluated computationally using multiple

in silico web based prediction tools and by segregation analysis. NOS3 and VEGF

gene polymorphisms were genotyped in 123 patients of ADPKD and 100 healthy

controls. Genotyping was carried out using the amplification refractory mutationspecific

polymerase chain reaction (ARMS-PCR) for NOS3 and restriction fragment

length polymorphism (RFLP) for VEGF gene polymorphisms. Comparison of allele,

genotype and haplotype frequencies between groups was done by using Chi-Square

( 2) test or Fisher's exact test.
By:  
Imprint:   Akhand Publishing House
Dimensions:   Height: 229mm,  Width: 152mm,  Spine: 12mm
Weight:   318g
ISBN:   9787238457455
ISBN 10:   7238457458
Pages:   234
Publication Date:  
Audience:   General/trade ,  ELT Advanced
Format:   Paperback
Publisher's Status:   Active

See Also

Patients with Autosomal Dominant Polycystic Kidney Disease

Utilization of Proteins from Kidney...

Khetan Shevkani

Paperback

$55.95  $47.68

Not in-store but you can order this

ADD +
Patients with Autosomal Dominant Polycystic Kidney Disease

Basic Surgical Skills

An Illustrated Guide

Graeme Downes

Hardback

$145 

Not in-store but you can order this

ADD +
Patients with Autosomal Dominant Polycystic Kidney Disease

Early Detection of Chronic Kidney...

Babitha Sujanna J

Paperback

$49.95  $42.07

Not in-store but you can order this

ADD +
Patients with Autosomal Dominant Polycystic Kidney Disease

Systemic Sclerosis

An Illustrated Guide to Manifestation...

Arun C Inamadar

Paperback

$94.99 

Not in-store but you can order this

ADD +
Patients with Autosomal Dominant Polycystic Kidney Disease

Basic Surgical Skills

An Illustrated Guide

Graeme Downes

Paperback

$56.99 

Not in-store but you can order this

ADD +
Patients with Autosomal Dominant Polycystic Kidney Disease

Kidney Disease

Heal Your Kidneys & Reverse Kidney...

Brain Hayes

Paperback

$22.95  $20.75

Not in-store but you can order this

ADD +