Our Genes, Our Choices: How Genotype and Gene Interactions Affect Behavior

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David Goldman (Clinical Director and Chief of the Laboratory of Neurogenetics, Office of the Clinical Director, Laboratory of Neurogenetics, NIAAA, Bethesda, MD, USA)

Our Genes, Our Choices

How Genotype and Gene Interactions Affect Behavior

David Goldman (Clinical Director and Chief of the Laboratory of Neurogenetics, Office of the Clinical Director, Laboratory of Neurogenetics, NIAAA, Bethesda, MD, USA)

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English

Academic Press Inc
29 September 2023

Genetics (non-medical); DNA & Genome

Our Genes, Our Choices: How Genotype and Gene Interactions Affect Behavior, Second Edition explains how the complexity of human behavior, including concepts of free will, derives from a relatively small number of genes which direct neurodevelopmental sequences. Are people free to make choices or do genes determine behavior? Paradoxically, the answer to both questions is ""yes,"" because of neurogenetic individuality, a new theory with profound implications. Here, author David Goldman uses judicial, political, medical, and ethical examples to illustrate that this lifelong process is guided by individual genotype, molecular and physiologic principles, as well as by randomness and environmental exposures.

Written in an authoritative yet accessible style, the book includes practical descriptions of the function of DNA, discusses the scientific and historical bases of genethics, and introduces the topics of epigenetics and the predictive power of behavioral genetics.

By: David Goldman (Clinical Director and Chief of the Laboratory of Neurogenetics Office of the Clinical Director Laboratory of Neurogenetics NIAAA Bethesda MD USA)
Imprint: Academic Press Inc
Country of Publication: United States
Edition: 2nd edition
Dimensions: Height: 229mm, Width: 152mm,
Weight: 450g
ISBN: 9780443221613
ISBN 10: 0443221618
Pages: 326
Publication Date: 29 September 2023
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

1. Introduction: Thou Mayest Choose 2. The Jinn in the Genome 3. 2B or Not 2B? 4. Stephen Mobley and His X-Chromosome 5. Dial Multifactorial for Murder: The Intersection of Genes and Culture 6. Distorted Capacity: The Measure of the Impaired Will 7. Distorted Capacity: Neuropsychiatric Diseases and the Impaired Will 8. Inheritance of Behavior and Genes “For Behavior 9. The Scientific and Historic Bases of Genethics 10. The World is Double Helical: DNA, RNA and Proteins, in a Few Easy Piece 11.The Stochastic Brain: From DNA Blueprint to Behavior 12. Reintroducing Genes and Behavior 13. Warriors and Worriers 14. How Many Genes Does it Take to Make a Behavior? 15. The Genesis and Genetics of Sexual Behavior 16. Gene by Environment Interaction 17. The Epigenetic Revolution 18.Time out for free will 19. The top-down neurogenesis of free will 20. Summing Up Genetic Predictors of Behavior

David Goldman received his B.S. from Yale University in 1974, graduating in only three years, and his M.D. degree from the University of Texas Medical Branch in 1978. He joined the intramural program of the National Institutes of Health in 1979, and is currently Clinical Director and Chief of the Laboratory of Neurogenetics of the National Institute on Alcohol Abuse and Alcoholism. Throughout his career, he has identified genetic factors responsible for inherited differences in behavior, his laboratory pioneering in functional genomics – how differences in DNA sequence translate into behavioral differences from molecule to intermediate brain processes to behavior. He is recipient of many awards for his research and is one of the most highly cited scientists in biological psychiatry. His laboratory is currently exploring the genetics of substance use disorders and related health problems.