Nanotechnology in Therapeutics: Basics and Trends

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Costas Demetzos (National and Kapodistrian University of Athens, Greece) Dennis Douroumis (University of Greenwich, UK)

Nanotechnology in Therapeutics

Basics and Trends

Costas Demetzos (National and Kapodistrian University of Athens, Greece), Dennis Douroumis (University of Greenwich, UK), Martin J. Snowden (University of Greenwich, UK) , Alfred Fahr (University of Greenwich)

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Hardback

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English

John Wiley & Sons Inc
12 September 2024

Therapy & therapeutics; Nanotechnology; Industrial chemistry; Chemical engineering

Series: Advances in Pharmaceutical Technology

Nanotechnology in Therapeutics

Comprehensive reference delivering a framework to develop and assess nanosystems that provide unique advantages in biomedical applications

Nanotechnology in Therapeutics explores the idea that by studying in depth the behavior of living organisms, especially the functionality of their cell membranes, we can develop and evaluate innovative bio-inspired nanosystems that are able to deliver small molecules, biomolecules like proteins, peptides, and other genetic material in terms of the production of new therapies and vaccines. The main concept promoted in this book is an integrated approach for producing new medicines following the nanotoxicity, biotoxicity, regulatory, and ethical guidelines, which are also covered in the book.

The book is divided into three parts. Part A provides an introduction and a historical overview of nanotechnology. Part B delves deeper into issues relating to lipid and polymeric nanostructures in medicine. Part C presents the regulatory landscape around nanotechnology and nanomedicine, while highlighting the need to keep an eye on emerging technologies such as artificial intelligence and machine learning. Overall, this book opens up biomedical applications for previously challenging drugs and drug targets.

Written by a highly qualified professor with significant pertinent research experience, Nanotechnology in Therapeutics includes discussion on:

Eukaryotic cell membranes, their structural properties, and the thermodynamic payload of their lipid bilayers The DLVO (Derjaguin, Landau, Verwey and Overbeek) theory as a scientific tool for studying the stability and the behavior of nanoparticles Liposomes, lipid nanoparticles, and solid lipid nanoparticles, as well as polymeric nanoparticles, like micelles, polymersomes, and dendrimers Issues in the approval process of nanomedicines by the regulatory agencies, such as complexity, chaos, and nonlinear dynamics

With comprehensive coverage of novel concepts that have the potential to transform how new medicines are designed and developed, Nanotechnology in Therapeutics is an essential resource on the subject for chemists in industry, as well as biomedical and pharmaceutical engineers.

By: Costas Demetzos (National and Kapodistrian University of Athens Greece)
Series edited by: Dennis Douroumis (University of Greenwich UK), Martin J. Snowden (University of Greenwich, UK), Alfred Fahr (University of Greenwich), Juergen Siepmann (University of Lille 2, France)
Imprint: John Wiley & Sons Inc
Country of Publication: United States
ISBN: 9781394274055
ISBN 10: 139427405X
Series: Advances in Pharmaceutical Technology
Pages: 304
Publication Date: 12 September 2024
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Forthcoming

Part A: Introduction to nanotechnology and to the physicochemical properties of nanosystems Chapter 1: Introduction to nanotechnology Chapter 2: Introduction to biophysics of nanosystems PART B: Diagnostics, Imaging and Therapeutics. Chapter 3: Nanomolecular diagnostics and imaging Chapter 4: Nanotechnology in therapeutics Chapter 5: Nanotechnology in Vaccines Part C: Nanotoxicity, regulatory landscape and approval processes for nanomedicines Chapter 6: Toxicity, safety, and adverse reactions of nanomedicines. Chapter 7: Regulatory landscape and approval process

Costas Demetzos is Professor of Pharmaceutical Nanotechnology at the National and Kapodistrian University of Athens. Currently, Prof. Demetzos serves as Director of the Laboratory of Pharmaceutical Technology, and since 2008 he serves as President of the Hellenic Pharmaceutical Society (HPS). His research interests include pharmaceutical nanotechnology, nanomedicine, and thermodynamics.