Molecular Analyses

Scott Orland Rogers (Bowling Green State University, Ohio, USA)

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English

CRC Press
26 August 2024

Biochemistry

Series: Molecular Genomics and Proteomics

DNA and RNA extraction methods from a variety of tissues and samples are now routine, including extraction from single cells. Many methods are now automated. Sequencing efficiency has reached the point where it is now possible to obtain gigabases of data, both quickly and inexpensively. Such methods permit the identification of gene versions, including those associated with disease (e.g. small nucleotide polymorphism analyses, or SNPs). The general public as well as clinicians can now access a wide variety of literature on the molecular bases of diseases, allowing them to better assess disease risks and treatments. This volume concentrates on medically-focused methods, and therefore the major audience will be medical professionals, students, and those involved in medically-related research endeavors. There are also papers in this volume dealing specifically with methods developed to analyze large sequence data sets. Many methods reviewed herein are more broadly applicable to other fields in biology, chemistry, bioinformatics, and bioengineering, and are intended for a broad readership.

Key Features

Summarizes nucleic acid extractions from a wide variety of tissues and cells

Describes processes of nucleic acid preservation

Reviews forensic sampling, detection of nucleic acids, and delivery of nucleic acids to multicellular organisms

Provides essential guidance for sequencing, sequence analysis, database searches, and phylogenetic analyses

Includes additional methods useful for analysis of nucleic acids and proteins

Related Titles

DeSalle, et al. Phylogenomics: A Primer (ISBN 978-0-3670-2849-7).

Jennings, W. B. Phylogenomic Data Acquisition: Principles and Practice (ISBN 978-0-3678-6980-9).

Wang, X. Next-Generation Sequencing Data Analysis (ISBN 978-1-4822-1788-9)

Sung, W.-K. Algorithms for Next-Generation Sequencing (ISBN 978-0-3676-5797-0)

Edited by: Scott Orland Rogers (Bowling Green State University Ohio USA)
Imprint: CRC Press
Country of Publication: United Kingdom
Dimensions: Height: 234mm, Width: 156mm,
Weight: 700g
ISBN: 9781032161907
ISBN 10: 1032161906
Series: Molecular Genomics and Proteomics
Pages: 361
Publication Date: 26 August 2024
Audience: College/higher education , Professional and scholarly , Primary , Undergraduate
Format: Paperback
Publisher's Status: Forthcoming

Scott Orland Rogers is a professor of molecular biology and evolution at Bowling Green State University, Bowling Green, Ohio. He received his PhD in plant molecular biology from the University of Washington, Seattle. He was an assistant professor and associate professor at the State University of New York College of Environmental Science and Forestry before moving to BGSU. He has taught courses in biology, botany, cell physiology, molecular biology, molecular genetics, bioinformatics, and molecular evolution. Research in his lab includes studies of microbes and nucleic acids preserved in ice, life in extreme environments, group I introns, molecular microbial phylogenetics, microbial metagenomics/metatranscriptomics, ancient DNA, and plant development.