Immuno-oncology and immunotherapy Part B

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Lorenzo Galluzzi (Assistant Professor of Cell Biology in Radiation Oncology, Department of Radiation Oncology, Weill Cornell Medical College, NY, USA) Norma Bloy

Immuno-oncology and immunotherapy Part B

Lorenzo Galluzzi (Assistant Professor of Cell Biology in Radiation Oncology, Department of Radiation Oncology, Weill Cornell Medical College, NY, USA), Norma Bloy, Maud Charpentier

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English

Academic Press Inc
01 December 2024

Oncology; Developmental biology; Molecular biology; Cellular biology (cytology)

Series: Methods in Cell Biology

Immuno-oncology and immunotherapy, Part B, Volume 191 in the Methods in Cell Biology series, highlights new advances, with this volume presenting chapters on a variety of topics, including Multiparametric flow cytometry study of human MDSCs, In vitro screening methods of novel immune checkpoint inhibitors related to T cell infiltration and anti-PD-1 resistance, Machine learning approach to assess brain metastatic burden in preclinical models, Cytofluorometric analysis of the maturation and activation of bone marrow-derived dendritic cells to assess immunogenic cell death, 3D agar colony inhibition assays to functionally evaluate HER2-targeting antibodies against human cancer cells elicited by vaccination in mice, and much more.

Additional sections cover Spatial immunophenotyping of FFPE tissues by imaging mass cytometry, Processing human colon cancer specimens for in vitro cytotoxicity assays, A xenograft model of metastatic colon cancer, A preclinical model of hepatic metastasis to instruct effective treatment modalities, Myeloid-derived suppressor cells: Identification and function, Measuring the impact of therapy-induced senescence on NK cell phenotypes in cancer, and Selective expansion of anti-tumor innate lymphocytes in long-term cultures after a single BCG pulse.

Volume editor: Lorenzo Galluzzi (Assistant Professor of Cell Biology in Radiation Oncology Department of Radiation Oncology Weill Cornell Medical College NY USA), Norma Bloy, Maud Charpentier
Imprint: Academic Press Inc
Country of Publication: United States
Dimensions: Height: 229mm, Width: 152mm,
ISBN: 9780443296161
ISBN 10: 0443296162
Series: Methods in Cell Biology
Pages: 236
Publication Date: 01 December 2024
Audience: Professional and scholarly , College/higher education , Undergraduate , Further / Higher Education
Format: Hardback
Publisher's Status: Active

1. Multiparametric flow cytometry study of human MDSCs Luis de la Cruz-Merino and Victor Sanchez-Margalet Sr. 2. In vitro screening methods of novel immune checkpoint inhibitors related to T cell infiltration and anti-PD-1 resistance Yanfeng Gao, Zhuouying He, Xiuman Zhou and Youmei Xiao 3. Machine learning approach to assess brain metastatic burden in preclinical models Romina Goldszmid 4. Cytofluorometric analysis of the maturation and activation of bone marrow-derived dendritic cells to assess immunogenic cell death Dmitri Krysko, Faye Naessens, Iuliia Efimova and Mariia Saviuk 5. 3D agar colony inhibition assays to functionally evaluate HER2-targeting antibodies against human cancer cells elicited by vaccination in mice Pier-Luigi Lollini, Francesca Ruzzi, Maria Sofia Semprini, Laura Scalambra, Stefania Angelicola, Chiara Cappello, Olga Maria Pittino, Patrizia Nanni and Arianna Palladini 6. Spatial immunophenotyping of FFPE tissues by imaging mass cytometry Barbara Maier 7. Processing human colon cancer specimens for in vitro cytotoxicity assays Sofia Mensurado Santos, Rafael Blanco Domínguez, Bruno Silva-Santos, Mariana Carreira and Leandro Barros 8. A xenograft model of metastatic colon cancer Sofia Mensurado Santos and Rafael Blanco Domínguez 9. A preclinical model of hepatic metastasis to instruct effetive treatment modalities Anna Mondino, Citro Antonio, Lorenzo Piemonti, Arianna Pocaterra, Chiara Gnasso, Tamara Canu, Anna Tosi, Antonio Rosato and Antonio Esposito 10. Myeloid-derived suppressor cells: Identification and function Lorenzo Moretta, Nicola Tumino, Maria Teresa Bilotta and Paola Vacca 11. Measuring the impact of therapy-induced senescence on NK cell phenotypes in cancer Marcus Ruscetti, Shreya Chowdhury, Katherine Murphy, Chaitanya Parikh, Kelly DeMarco and Lin Zhou 12. Selective expansion of anti-tumour innate lymphocytes in long-term cultures after a single BCG pulse Mar Vales-Gomez

Lorenzo Galluzzi is Assistant Professor of Cell Biology in Radiation Oncology at the Department of Radiation Oncology of the Weill Cornell Medical College, Honorary Assistant Professor Adjunct with the Department of Dermatology of the Yale School of Medicine, Honorary Associate Professor with the Faculty of Medicine of the University of Paris, and Faculty Member with the Graduate School of Biomedical Sciences and Biotechnology of the University of Ferrara, the Graduate School of Pharmacological Sciences of the University of Padova, and the Graduate School of Network Oncology and Precision Medicine of the University of Rome “La Sapienza. Moreover, he is Associate Director of the European Academy for Tumor Immunology and Founding Member of the European Research Institute for Integrated Cellular Pathology. Galluzzi is best known for major experimental and conceptual contributions to the fields of cell death, autophagy, tumor metabolism and tumor immunology. He has published over 450 articles in international peer-reviewed journals and is the Editor-in-Chief of four journals: OncoImmunology (which he co-founded in 2011), International Review of Cell and Molecular Biology, Methods in Cell biology, and Molecular and Cellular Oncology (which he co-founded in 2013). Additionally, he serves as Founding Editor for Microbial Cell and Cell Stress, and Associate Editor for Cell Death and Disease, Pharmacological Research and iScience.