This detailed collection covers how the biological functions of histone deacetylases (HDACs) and histone acetyltransferases (HATs) can be detected in various experimental settings, both in vivo and in vitro. The book also covers the generation and specificity of deacetylase inhibitors and how such agents can be used to test experimental hypotheses. Written for the popular Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, HDAC/HAT Function Assessment and Inhibitor Development: Methods and Protocols serves as an ideal guide to this vital area of study.
Edited by:
Oliver H. Krämer Imprint: Humana Press Inc. Country of Publication: United States Edition: Softcover reprint of the original 1st ed. 2017 Volume: 1510 Dimensions:
Height: 254mm,
Width: 178mm,
Spine: 22mm
Weight: 8.062kg ISBN:9781493982264 ISBN 10: 1493982265 Series:Methods in Molecular Biology Pages: 415 Publication Date:20 June 2018 Audience:
Professional and scholarly
,
Undergraduate
Format:Paperback Publisher's Status: Active