Handbook of Epigenetics: The New Molecular and Medical Genetics

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Trygve O Tollefsbol (Distinguished Professor of Biology, University of Alabama at Birmingham, AL, USA)

Handbook of Epigenetics

The New Molecular and Medical Genetics

Trygve O Tollefsbol (Distinguished Professor of Biology, University of Alabama at Birmingham, AL, USA)

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English

Academic Press Inc
12 September 2022

Genetics (non-medical); DNA & Genome

Handbook of Epigenetics: The New Molecular and Medical Genetics, Third Edition provides a comprehensive analysis of epigenetics, from basic biology to clinical application. This new edition has been fully revised to cover the latest and evolving topics in epigenetics, with chapters updated and new chapters added on topics such as single-cell epigenetics, DNA methylation clocks in age-related diseases, transposable elements and epigenetics, X chromosome inactivation, and the epigenetics of drug addiction, among other topics. Throughout this edition, greater emphasis falls on epigenomic analyses and incorporating multi-omics approaches rather than gene-specific analyses.

In addition, this edition has also been enhanced with step-by-step instructions in research methods, as well as easy-to-digest disease case studies and clinical trials that provide context and applied examples of recent advances in disease understanding and epigenetic therapeutics. These features empower researchers to reproduce the approaches and studies discussed and aid clinical translation. Live links across chapters tie in relevant external datasets and resources.

Edited by: Trygve O Tollefsbol (Distinguished Professor of Biology University of Alabama at Birmingham AL USA)
Imprint: Academic Press Inc
Country of Publication: United Kingdom
Edition: 3rd edition
Dimensions: Height: 276mm, Width: 216mm,
Weight: 2.400kg
ISBN: 9780323919098
ISBN 10: 032391909X
Pages: 918
Publication Date: 12 September 2022
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

Dr. Tollefsbol is a Distinguished Professor of Biology and a Senior Scientist in the O’Neal Comprehensive Cancer Center, Integrative Center for Aging Research, Nutrition Obesity Research Center, University Wide Microbiome Center, and the Comprehensive Diabetes Center at the University of Alabama at Birmingham (UAB). He is Director of the UAB Cell Senescence Culture Facility which he established in 1999. Dr. Tollefsbol trained as a Postdoctoral Fellow and Assistant Research Professor with members of the National Academy of Science at Duke University and the University of North Carolina. He earned doctorates in molecular biology and osteopathic medicine from the University of North Texas Health Sciences Center and his bachelor’s degree in Biology from the University of Houston. He has received prior funding from the NCI, NHLBI, NIMH and other federal institutes as well as the Glenn Foundation for Medical Research, Susan G. Komen for the Cure, the American Federation for Aging Research (AFAR), and the American Institute for Cancer Research (AICR) among many other sources.