Genetics and Genomics of Eye Disease: Advancing to Precision Medicine

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Xiaoyi Raymond Gao, PhD (Associate Professor, Departments of Ophthalmology and Visual Science and Biomedical Informatics, Division of Human Genetics, The Ohio State University, Columbus, OH, USA)

Genetics and Genomics of Eye Disease

Advancing to Precision Medicine

Xiaoyi Raymond Gao, PhD (Associate Professor, Departments of Ophthalmology and Visual Science and Biomedical Informatics, Division of Human Genetics, The Ohio State University, Columbus, OH, USA)

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English

Academic Press Inc
13 September 2019

Genetics (non-medical); DNA & Genome

Genetics and Genomics of Eye Disease: Advancing to Precision Medicine thoroughly examines the latest genomics methods for studying eye disease, including complex eye disorders associated with multiple genes. GWAS, WES, WGS, RNA-sequencing, and transcriptome analysis as employed in ocular genomics are discussed in-depth, as are genomics findings tied to early-onset glaucoma, strabismus, age-related macular degeneration, adult-onset glaucoma, diabetic retinopathy, keratoconus, and leber congenital amaurosis, among other diseases. Research and clinical specialists offer guidance on conducting preventative screenings and counseling patients, as well as the promise of machine learning, computational statistics and artificial intelligence in advancing ocular genomics research.

Edited by: Xiaoyi Raymond Gao PhD (Associate Professor Departments of Ophthalmology and Visual Science and Biomedical Informatics Division of Human Genetics The Ohio State University Columbus OH USA)
Imprint: Academic Press Inc
Country of Publication: United States
Dimensions: Height: 235mm, Width: 191mm,
Weight: 770g
ISBN: 9780128162224
ISBN 10: 0128162228
Pages: 383
Publication Date: 13 September 2019
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

Dr. Xiaoyi “Raymond Gao is an Associate Professor in the Department of Ophthalmology and Visual Sciences, the Biostatistics and Genetic Analysis Core Director of the P30 departmental core grant, and the Director of the Quantitative Ocular Genomics Laboratory at the University of Illinois at Chicago (UIC). He is an experienced statistical geneticist and leader of ocular genomics research for multiple National Eye Institute funded projects on glaucoma in Hispanics/Latinos, steroid-induced ocular hypertension, and ocular biostatistics and genetic analysis. His goal is to advance genomic-based discoveries in ocular diseases and traits and to reduce the burden of blindness. Dr. Gao has a unique interdisciplinary background in bioinformatics, statistics and genetics. After receiving his PhD in Bioinformatics-Statistics from North Carolina State University, Dr. Gao completed his post-doctoral training in statistical genetics at Duke University Center for Human Genetics and the John P. Hussman Institute of Human Genomics at the University of Miami. He then worked at the Division of Statistical Genomics at Washington University in St. Louis and the Department of Ophthalmology and Preventive Medicine at the University of Southern California before joining UIC Ophthalmology. Dr. Gao has published widely on a variety of topics in vision research, statistical genomics, and genetic epidemiology.

Reviews for Genetics and Genomics of Eye Disease: Advancing to Precision Medicine

""Regardless, the book summarises a significant combination of digital inputs – genomic data, fundus images, optical coherence tomography and others – aimed to synthesize enormous information over the coming decade, likely useful to both clinicians and researchers in the field of ocular medicine."" --Euretina Brief ""This book is highly specialized and, by nature, it will be difficult to compare. Clearly there are publications in the literature that deal with photographic documentation of genetic eye disorders. This is not an atlas; it is a concise review of knowledge. Great work and congratulations to the contributors and Dr. Gao."" --Doody