Gwenola Burgot, Pharmacist, PhD, formerly Professor in Analytical Chemistry, Faculty of Pharmaceutical and Biological Sciences of University of Rennes 1. Scientific adviser for the collection database ""Techniques de l’Ingénieur"". Her research interests and publications involve the determination by continuous adiabatic titration calorimetric method of physicochemical equilibrium, water/n-octanol kinetic and thermodynamic parameters of transfer of drugs and the optimization of analytical methods for quantitative analysis of drugs in pure form or formulations. Jean-Louis Burgot, Pharmacist, PhD in organic chemistry and PhD in analytical chemistry – thermometric titrimetry, formerly Professor in Analytical Chemistry, Faculty of Pharmaceutical and Biological Sciences of University of Rennes 1. His research interests and publications involve the synthesis and study of the physico-chemical properties of 1,2-Dithiole-3-thiones and derivatives, and the determination of thermodynamic and kinetic constants of pharmacologically active compounds. He has published seven books in French and English.