This issue of Hematology/Oncology Clinics will focus on Gene Therapy. Topics include, but are not limited to Historical Perspective and Current Renaissance, Integrating Vectors, Nonintegrating Vectors, Gene Editing, Conditioning Therapies for Autologous HSCT, Approaches to Immunodeficiency, Approaches to Hemoglobinopathy, Approaches to Hemophilia, Hematopoietic Gene Therapies for Neurologic and Metabolic Disease, Gene Therapy Approaches to HIV and other Infectious Diseases, HSC Approaches to Cancer, and Gene Modified T Cell Therapies for Cancer.
Hematology/Oncology Clinics Gene Therapy Preface: Gene Therapy Historical Perspective on the Current Renaissance for Hematopoietic Stem Cell Gene Therapy Integrating Vectors for Gene Therapy and Clonal Tracking of Engineered Hematopoiesis Nonintegrating Gene Therapy Vectors In Vivo Hematopoietic Stem Cell Transduction Therapeutic Gene Editing Safety and Specificity Gene Editing: Regulatory and Translation to Clinic Opening Marrow Niches in Patients Undergoing Autologous Hematopoietic Stem Cell Gene Therapy Gene Therapy Approaches to Immunodeficiency Gene Therapy Approaches to Hemoglobinopathies Gene Therapy for Hemophilia Hematopoietic Gene Therapies for Metabolic and Neurologic Diseases Gene Therapy Approaches to Human Immunodeficiency Virus and Other Infectious Diseases Hematopoietic Stem Cell Approaches to Cancer Gene Modified T Cell Therapies for Hematological Malignancies