Fundamentals of Oral Histology and Physiology is a landmark new text streamlining the essentials of histology and physiology into one clinically accessible textbook. Written for predoctoral dental students, the book brings together structure, function, and clinical correlations for maximum retention and ease of use.
Assuming a background in basic biologic sciences, this text focuses on the histology and physiology that students need to know to practice dentistry and to understand and evaluate the current literature, without repeating basic information learned in other courses. Fundamentals of Oral Histology and Physiology concentrates on Oral Structures and Features, including Development, Teeth, Tooth and Jaw Support, Mucosal Structure and Function, and Effectors.
Contributor List viii Preface ix 1 Oral Structures and Tissues 1 Arthur R. Hand and Marion E. Frank The oral cavity 1 Oral mucosa 3 Teeth 4 Supporting tissues of the teeth 5 Salivary glands 5 Temporomandibular joint 7 PART I DEVELOPMENT Chapter 2 Development of the Head, Face, and Mouth 13 Joseph A. Grasso Introduction 13 Early events establishing the head region 13 Development of the pharyngeal region and the pharyngeal arches 19 Development of the face and jaws 26 Clinical correlations 40 Chapter 3 Tooth Development 44 Martyn T. Cobourne and Paul T. Sharpe The histology of tooth development 44 The biology of early tooth development 47 The molecular control of early tooth development 51 Clinical correlations 54 PART II THE TEETH Chapter 4 Enamel 63 Arthur R. Hand Enamel structure, composition, and properties 63 Enamel formation 69 Clinical correlations 79 Chapter 5 Dentin, Pulp, and Tooth Pain 85 Michel Goldberg Evolution of dental structures 85 Dentin structure and composition 85 Dentin formation 90 Pulp structure and function 97 Pulp vascularization 100 Innervation of the dentin and pulp 102 Mechanisms of tooth pain 103 Clinical correlations 105 PART III TOOTH AND JAW SUPPORT Chapter 6 Structure and Physiology of the Periodontium 115 Arthur R. Hand Cementum structure, composition and formation 115 Periodontal ligament structure and function 122 Sensory functions of the periodontal ligament 128 Structure and function of alveolar bone 128 Clinical correlations 132 Chapter 7 Tooth Eruption and Shedding 136 Arthur R. Hand Normal eruption sequence 136 Histology of tooth eruption 138 Cellular and molecular mechanisms of tooth eruption 144 Structure and formation of the dentogingival junction 144 Clinical correlations 147 Chapter 8 Temporomandibular Joint 149 Felipe Porto Structure of the TMJ 149 TMJ histology 153 Function (biomechanics) of the TMJ 154 Clinical correlations 156 PART IV MUCOSAL STRUCTURE AND FUNCTION Chapter 9 Oral Mucosa and Mucosal Sensation 165 Ellen Eisenberg, Easwar natarajan, and Bradley K. Formaker The oral cavity - anatomy 165 Oral mucosa 169 Stratified squamous epithelium – general principles \and differentiation 171 The epithelial-stromal interface 175 Non-keratinocytes 176 Types of oral mucosa 176 Oral sensation 179 Clinical correlations 182 Chapter 10 Chemoreception and Perception 191 Marion E. Frank Taste 191 Smell 205 Oral chemosensation 216 Clinical correlations 217 PART V ORAL EFFECTORS Chapter 11 Salivary Glands, Salivary Secretion, and Saliva 223 Arthur R. Hand Structure 223 Development 230 Major glands 231 Minor glands 232 Salivary secretion 233 Saliva composition and function 235 Diagnostic and forensic uses of saliva 238 Clinical correlations 238 Chapter 12 Orofacial Pain, Touch and Thermosensation, and Sensorimotor Functions 241 Barry J. Sessle Sensory functions 241 Sensorimotor functions and motor control 251 Clinical correlations 258 Chapter 13 Anatomy and Physiology of Speech Production 263 Janet Rovalino Phonation and vocal tract modulations 263 Articulation 267 Clinical correlations 269 Index 274
Arthur R. Hand, DDS, is Professor of Craniofacial Sciences and Cell Biology at the University of Connecticut Health Center. He has more than 180 peer-reviewed publications, was the founding editor of Advances in Dental Research, and serves or has served on the editorial boards of The Journal of Oral Science, Journal of Dental Research, Journal of Histochemistry and Cytochemistry, Biotechnic & Histochemistry and Acta Histochemica et Cytochemica. Prior to his position in academia, he spent 21 years as a scientist in the intramural research program of the National Institute of Dental and Craniofacial Research. He has directed a course for 1st year dental students on Oral Histology and Physiology for more than 15 years. Marion E. Frank, PhD, is Professor of Oral Health and Diagnostic Sciences and Director of the Center for Chemosensory Sciences at the University of Connecticut Health Center. Her basic and clinical research in the chemical senses is reported in more than 65 peer-reviewed publications and she has served on the editorial boards of the Journal of General Physiology, Journal of Neurophysiolgy and Chemical Senses. She obtained her doctorate from Brown University and began her academic career at the Rockefeller University before joining the School of Dental Medicine to teach Oral Physiology and Neuroscience and lead the research team of the NIH-sponsored Connecticut Chemosensory Clinical Research Center in Farmington.
