From Loss to Memory

Behind the Discovery of Synaptic Pruning

Anna Huttenlocher (University of Wisconsin, Madison)

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Hardback

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English

Cambridge University Press
06 July 2023

Psychology; History of medicine; Neurology & clinical neurophysiology; Neurosciences; Developmental biology

How do the billions of connections between neurons in our brain change as we learn and remember? This is the story of the discovery and the discoverer of synaptic pruning, the process of synapse elimination central to making us who we are. Taking the reader from Professor Peter Huttenlocher's childhood in wartime and post-war Germany to his emigration to the US to reunite with his mother and the launch and progress of a career in medicine and research, we uncover the motivations and process of scientific discovery that led to an unexpected leap in our understanding of the human brain. Decades after the discovery, the importance of synaptic pruning to early learning, autism, schizophrenia, Alzheimer's disease and other conditions are now in the process of being uncovered.

By: Anna Huttenlocher (University of Wisconsin Madison)
Imprint: Cambridge University Press
Country of Publication: United Kingdom
Dimensions: Height: 240mm, Width: 163mm, Spine: 14mm
Weight: 400g
ISBN: 9781009267052
ISBN 10: 1009267051
Pages: 150
Publication Date: 06 July 2023
Audience: General/trade , ELT Advanced
Format: Hardback
Publisher's Status: Active

Physician scientist Anna Huttenlocher is a Professor at University of Wisconsin, Madison and a member of the National Academy of Medicine. Her laboratory studies cell migration in inflammation and cancer. She directed the MD-Ph.D. program at UW-Madison and is a committed mentor to the next generation of physicians and biomedical scientists.

Reviews for From Loss to Memory: Behind the Discovery of Synaptic Pruning

'Anna Huttenlocher has written a fascinating book and an important biography of her father. [It] poses some deep questions about where science comes from, and provides some useful suggestions about how we might promote a healthier scientific society in the future.' Christopher Walsh, Lancet Neurology