Fatal Jump

Tracking the Origins of Pandemics

Leslie Reperant

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Hardback

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English

Johns Hopkins University Press
21 March 2023

Public health & preventive medicine; Biology, life sciences; Ecological science, the Biosphere; Evolution; The environment

Exploring the fateful chains of events that gave rise to humanity's infectious diseases and pandemics.

Why do global pandemics materialize? To address this question, we must delve into the world of pathogens that transcend their original host species and jump into new ones. Most pathogens fail to initiate infection or spread in the population when they jump. Only a few sustain onward chains of transmission, and even fewer sustain these indefinitely. Yet the rare pathogens that do make the leap have caused many of humanity's most dangerous infectious diseases.

In Fatal Jump: Tracking the Origins of Pandemics, veterinary disease ecologist Dr. Leslie Reperant investigates mysteries such as how African-originated monkeypox left its home continent, why COVID-19 could threaten measles control, and how pigs' fondness for mangoes enabled the deadly Nipah virus to spread. She shares behind-the-scenes insights into hugely destructive pathogens carried by rats, bats, ticks, and mosquitoes, as well as lesser-known vectors such as prairie dogs and camels. Drawing from the latest research, she discusses whether we can predict these deadly jumps before they happen and what factors—including environmental change, population dynamics, and molecular evolution—enable a zoonotic disease to reach full pandemic status. Rich with recent scientific discoveries and emerging theories, this book spans a diverse range of disciplines, weaving their insights into a holistic view of infectious disease.

With new pathogens emerging at an alarming pace, Fatal Jump reorients our perspective on pandemics from a human-centered standpoint to the bigger picture. We will understand what actions are necessary to control emergence only by recognizing the increasingly global nature of human society and the connections between the planet's environmental health and our own health.

By: Leslie Reperant
Imprint: Johns Hopkins University Press
Country of Publication: United States
Dimensions: Height: 229mm, Width: 152mm, Spine: 37mm
Weight: 953g
ISBN: 9781421446363
ISBN 10: 1421446367
Pages: 520
Publication Date: 21 March 2023
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

Preface Part I: On the Origin of Plagues 1. Parasites, Pathogens & the Tree of Life 2. The Red Queen & the Court Jester 3. Heirlooms & Souvenirs 4. New Alliances & Painful Scars Part II: The Ghosts of Plagues Past 5. Medieval Outcasts 6. Cryptic Plagues 7. Disease Conquests 8. Conquering Diseases Part III: Emergence 9. Heavy Harvests 10. Going Global 11. Tipping Points Epilogue: One Health and the Mad Hatter Acknowledgements Bibliography

Leslie Reperant is a Doctor of Veterinary Medicine and holds a PhD in ecology and evolutionary biology from Princeton University. She has published her research on emerging infectious diseases in leading scientific journals, including The Lancet and Science.

Reviews for Fatal Jump: Tracking the Origins of Pandemics

Fatal Jump is indeed a journey, by leaps and bounds around the world and through time, that leads the reader to examine the extraordinary circumstances--evolutionary, ecological, and otherwise--that converged and gave birth to some of our most wicked plagues and pandemics, including the latest one. --The Page 99 Test