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English
Academic Press Inc
05 December 2022

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*Selected for Doody’s Core Titles® 2024 in Clinical Genetics
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Epigenetics in Organ Specific Disorders, a new volume in the Translational Epigenetics series, provides a foundational overview and nuanced analysis of epigenetic gene regulation distinct to each organ type and organ specific disorders, fully elucidating the epigenetics pathways that promote and regulate disease. After a brief introduction, chapter authors compare epigenetic regulations across normal and disease conditions in different organ tissues, exploring similarities and contrasts. The role of epigenetic mechanisms in stem cells, cell-matrix interactions and cell proliferation, cell migration, cellular apoptosis, necrosis, pyknosis, tumor suppression, and immune responses across different organ types are examined in-depth.

Organ specific epigenetic mechanisms and biomarkers of early use in developing drugs, which can selectively target the organ of interest, are also explored to enable new precision therapies.
Volume editor:   , , , , ,
Imprint:   Academic Press Inc
Country of Publication:   United States
Dimensions:   Height: 235mm,  Width: 191mm, 
Weight:   1.340kg
ISBN:   9780128239315
ISBN 10:   012823931X
Series:   Translational Epigenetics
Pages:   666
Publication Date:  
Audience:   Professional and scholarly ,  Undergraduate
Format:   Paperback
Publisher's Status:   Active

Dr. Chandra S. Boosani is an Assistant Professor at the Genetics, Epigenetics & Molecular Biology Lab, within the Department of Translational Research, at the College of Osteopathic Medicine, Pacific Western University School of Health Sciences, CA, U.S.A. His research focuses on developing and testing anticancer proteins, and identifying mechanisms of epigenetic drug action, with emphasis on developing recombinant proteins, drug testing in live mice, and analyzing sequencing data. Dr. Boosani has published in such peer reviewed journals as Seminars in Cancer Biology, Blood, Pharmaceuticals, Gene Regulation and Systems Biology, and Protein Expression and Purification. Ritobrata Goswami is a Assistant Professor in the School of Bioscience, IIT Kharagpur, West Bengal, India.

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