Dr Richard W Newton FRCPCH FRCP is a consultant paediatric neurologist of over 30 years' experience. He was President of the European Association of Learning Disability Medicine from 1997 to 2001 and President of the British Paediatric Neurology Association from 2001 to 2005. His special research interests are febrile seizures, neuroimmunology, headache and the medical aspects of Down syndrome. He is the father of a young man with Down syndrome and a member of the UK Down syndrome Association. Dr Liz Marder MRCP(UK) FRCPCH has been a Consultant Community Paediatrician and Lead Clinician for Children and Young People at Nottingham Children's Hospital since 1993. She runs the Nottingham Down Syndrome Children's Services. She is a founder member of the Down Syndrome Medical Interest Group (UK and Ireland) and medical advisor to the UK Down Syndrome Association. Dr Marder has been instrumental in developing resources on the medical aspects of Down syndrome including a special insert on Down syndrome for the UK Personal Child Health Record growth charts. Dr Shiela C Puri MRCP FRCPCH(UK) is a Consultant Community Paediatrician at the Child Development Centre in Leeds and an Honorary Senior Lecturer at the University of Leeds, Department of Paediatrics and Child Health. She has been a consultant paediatrician since 1990. Dr Puri established a one-stop multidisciplinary clinic for children with Down syndrome in Leeds to offer a holistic model of care to the children. In 2014 she was appointed Vice-chair elect of the Down Syndrome Medical Interest Group.