Disease X

The 100 Days Mission to End Pandemics

Kate Kelland, Tony Blair

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English

Canbury Press
02 February 2023

Public health & preventive medicine; Diseases & disorders; Popular science

Exclusive look inside global virus battle.

A must-read account of how international scientists and global public health leaders are preparing the world to contain outbreaks of new and re-emerging infectious diseases before they become pandemics like COVID-19.

DISEASE X is the codename given by the World Health Organisation to a pathogen currently unknown to science that could cause havoc to humankind. Emerging infections are sending us multiple warnings that another Disease X is looming. We've had SARS in 2002, H5N1 bird flu in 2004, H1N1 'swine flu' in 2009, MERS in 2012, Ebola in 2014, Zika in 2015 and now COVID-19. These events are not freak events, but are happening continually, and at an increasing cadence.

Written by a long-standing ex-Reuters global health and science correspondent, DISEASE X will use privileged access to the body leading international efforts to control viruses, the Coalition for Epidemic Preparedness Innovations (CEPI), and its CEO, Dr Richard Hatchett. CEPI seed-funded three successful COVID vaccines, including Astra-Zeneca and Moderna.

DISEASE X will explore the emergence of the novel coronavirus and the crisis it caused, analysing the responses of global health organisations and experts, including the WHO, national governments such as Britain, China and the USA, COVAX, the global vaccine allocation facility, pharmaceutical companies, and leading research scientists. Weaving in insights from the likes of Bill Gates, Sir Jeremy Farrar, Dr Anthony Fauci and Sir Patrick Vallance, the book will explain how the world's public health scientists are embarking on a 100 Days Mission to snuff out future threats before they become deadly pandemics. This is the inside story written for the public.

By: Kate Kelland
Foreword by: Tony Blair
Imprint: Canbury Press
Country of Publication: United Kingdom
Dimensions: Height: 234mm, Width: 156mm, Spine: 30mm
Weight: 450g
ISBN: 9781912454952
ISBN 10: 1912454955
Pages: 206
Publication Date: 02 February 2023
Audience: General/trade , College/higher education , Professional and scholarly , ELT Advanced , Primary
Format: Hardback
Publisher's Status: Out of Stock Indefinitely

Foreword by Sir Tony Blair. The former British Prime Minister warns that nations should not forget the risk of pandemics following the recovery from Covid-19 Introduction: Meet Disease X. Disease X is the World Health Organization's term for the next potential big pandemic. Previous examples include Ebola, Zika and SARS. The world has a '100 Days Mission' to combat the next Disease X 1. Prepare to be Scared. Pandemics are increasing in frequency and seriousness. Novel viruses can spread in unusual ways and their growth can be exponential. 2. Prepare to Move Fast. The increasing arrival of new communicable diseases such as SARS, MERS and Zika (not to mention Covid-19) means that the world's countries must be ready to act quickly: 'Making quick, decisive moves in the early stage of a rapidly spreading disease outbreak is a prerequisite for getting ahead of a potential pandemic. 3. Prepare to Take Risks. The necessity of pump priming the development of vaccines by pharmaceutical companies to maximise the chances of effective preventative medicine. Sometimes this money will be wasted; often it will halt the exponential spread of a virus that could wreak devastation on human populations. 4. Prepare to Share. Covid-19 showed that international cooperation is essential to thwart the growth of diseases. Public health leaders such as CEPI's Richard Hatchett devised an internationally fair system for sharing vaccines, COVAX. 5. Prepare to Listen. Governments should listen to health experts who are familiar with the spread of infectious diseases. Unfortunately, Britain's Prime Minister during Covid-19, Boris Johnson, did not listen - or, at least, did not act quickly enough. 6. Prepare to Fail. Many vaccine trials will fail. The search for a vaccine for HIV has, for instance, repeatedly failed. However, the attempts to develop a vaccine for HIV have led to breakthroughs in the development of vaccines for other diseases. Scientific advancement is not linear and requires patience. 7. Prepare to Spend Money. Pandemics cost trillions of dollars. Preventing them through the timely development of vaccines and other preventative measures costs much less. If the world spent a fraction of the money it spends on the military annually (almost $2 trillion in 2020) on public health instead, the world's population would benefit tangibly and manifestly. 8. Prepare for the Next One... Because it's coming. 9. 2027: A Pandemic is Thwarted. Imagining how the 100 Days Mission could work in the future, by assessing an outbreak of a pandemic in Asia in the future Postscript Resources and Further Reading Acknowledgements End Notes Index

Kate Kelland is an award-winning global health correspondent formerly at Reuters. She is now chief scientific writer at the Coalition for Epidemic Preparedness Innovations in London. During 30 years in journalism, she set the agenda in global health and science coverage. In 2017, she won the London Foreign Press Association Science Story of the Year award for her investigative reporting on the International Agency for Research on Cancer. In 2016, she won the Medical Journalists Association’s Feature of the Year award for a piece on the critical challenge facing the WHO – to heal itself. She was UK winner of the European Health Prize for Journalists in 2011, 2012 and 2013. Tony Blair is Executive Chairman of the Tony Blair Institute for Global Change. He was Prime Minister of the United Kingdom from 1997 to 2007 and leader of the Labour Party between 1994 and 2007. He led the Labour Party to three consecutive general election victories, in 1997, 2001 and 2005, becoming the longest-serving prime minister in modern times after Margaret Thatcher. The Tony Blair Institute for Global Change aims to equip political leaders around the world to build prosperous, open and inclusive societies.

Reviews for Disease X: The 100 Days Mission to End Pandemics

"DISEASE X: CAN THE NEXT PANDEMIC VACCINE BE DEVELOPED IN 100 DAYS? Editorial Team, Vaccines Today March 6th, 2023 Disease X. It’s the placeholder name given to a hypothetical new human disease with the potential to trigger a pandemic. The concept was developed by the World Health Organization in 2018 as a way to plan and prepare for viral threats. A new form of influenza, a novel coronavirus, a mutated measles-like virus ? there was no way of knowing for sure where the threat would come from, but the response would be similar. Now, three years after a real pandemic, caused by SARS-CoV-2, a new book looks at what went well, and what went wrong, in the global response. Kate Kelland, Chief Scientific Writer at the Coalition for Epidemic Preparedness Innovations (CEPI) and previously an award-winning journalist at Reuters, has interviewed scientists and decision-makers for DISEASE X – The 100 Days Mission to End Pandemics. The result is a fascinating and informed exploration of global health security, and a broadly encouraging assessment of how to prevent pandemics. Carry on reading: https://www.vaccinestoday.eu/stories/disease-x-can-the-next-pandemic-vaccine-be-developed-in-100-days/ “Covid-19 will not be the last pandemic to cause havoc. Disease X sets out how a mystery pathogen of the future could be contained before it goes global, but only if lessons are learned from SARS-CoV-2 and other global disease threats. ""An engaging, accessible and ultimately optimistic account of how nations, institutions and the scientific community responded to Covid, and how they could work together in future.” – Fergus Walsh, BBC Medical Editor “As Kelland argues cogently, fear of the next outbreak should not paralyse us but instead galvanise us into making sure the terrible toll of Covid-19 is not repeated. ""Just as we do not wait for a formal declaration of war before building up military capabilities, we must be prepared to invest in rapid surveillance, financing, vaccines, treatments and manufacturing capacity ahead of time. ""Disease X is a valuable policy roadmap in a world custom-built for pandemics.” – Anjana Ahuja, co-author with Jeremy Farrar of Spike: The Virus Vs The People “Disease X delivers a sobering message. It also offers hope that when the next deadly virus with pandemic potential emerges – not if – the world will be much better equipped to respond. ""With access to key players on the frontlines, Disease X takes us inside the effort to prevent future outbreaks from exploding into global disasters. People remember wars. They forget about pandemics. ""Three years after the Covid crisis erupted, we’re desperate to move on. But this important book outlines why it will be vital to keep pandemic threats at the top of our priority list for decades to come.” – James Paton, former Health Correspondent for Bloomberg News"