"It is estimated that 80 to 90% of drugs under development never make it to the marketplace due to insufficient clinical activity, unacceptable toxicity, rapid appearance of drug resistance, or other factors that should be, at least partially, predictable from preclinical testing. This new text asks the question, ""How can we use computational methods to improve the success rate in drug development?"" Computer Techniques in Preclinical and Clinical Drug Development shows how modeling makes it possible to extract the maximum amount of information and predictive value from preclinical data. Computer modeling methods from the areas of pharmacokinetics, pharmacodynamics, cytokinetics, and inhibition kinetics of multi-enzyme pathways are all discussed in this unique reference source."
By:
Robert C. Jackson Imprint: CRC Press Country of Publication: United Kingdom Dimensions:
Height: 234mm,
Width: 156mm,
Weight: 453g ISBN:9780367401283 ISBN 10: 0367401282 Pages: 256 Publication Date:07 October 2019 Audience:
Professional and scholarly
,
Undergraduate
Format:Paperback Publisher's Status: Active