Edited by Graham R. Foster PhD, FRCP, Professor of Hepatology, The Blizard Institute, Barts and The London School of Medicine, Queen Mary University of London, London, UK. K. Rajender Reddy MD, FACP, FACG, FRCP, FAASLD, Ruimy Family President's Distinguished Professor of Medicine, Professor of Medicine in Surgery, Director of Hepatology, Director of Viral Hepatitis Center, Medical Director of Liver Transplantation, University of Pennsylvania, Philadelphia, PA, USA.