Since the first edition was published in 2009, there have been significant advances in diagnostics and management of viral infections, as well as newly discovered viruses such as SARS-CoV-2 and Zika virus. This new edition provides up-to-date information on the key developments in clinical and diagnostic virology, especially molecular diagnosis, with guidance on new molecular and bedside tests. Effective antiviral treatments and novel combinations of treatments recently introduced are covered in depth. Infection control precautions and pandemic preparedness are discussed, with a focus on recent outbreaks. As with the first edition, coverage is succinct and practical with easily accessible information in algorithms and tables, and standardised chapter layouts organised from A to Z. This is an ideal introduction to complex topics for healthcare trainees, as well as a handy and easily accessible reference for more experienced hospital clinicians and primary care physicians.
Preface; Acknowledgements; List of abbreviations; Introduction: basic virology; Section 1: Individual Viruses: 1. Adenoviruses; 2. Arboviruses; 3. Cytomegalovirus; 4. Epstein-Barr virus; 5. Enteroviruses; 6. Hepatitis A virus; 7. Hepatitis B and D viruses; 8. Hepatitis C virus; 9. Hepatitis E virus; 10. Herpes simplex virus; 11. HIV and AIDS; 12. Human coronaviruses (including Covid-19, SARS and MERS); 13. Human herpesviruses types 6, 7 and 8; 14. Human metapneumovirus; 15. Human T-cell leukaemia viruses; 16. Influenza viruses; 17. Measles virus; 18. Mumps virus; 19. Noroviruses; 20. Papilloma and polyoma viruses; 21. Parainfluenza viruses; 22. Parvovirus B19; 23. Poxviruses; 24. Rabies virus; 25. Respiratory syncytial virus; 26. Rhinoviruses; 27. Rotaviruses; 28. Rubella virus; 29. Varicella-zoster virus; Section 2: Other Related Agents; 30. Chlamydia; 31. Toxoplasma gondii; 32. Transmissible spongiform encephalopathies (CJD and vCJD); Section 3: Clinical Syndromes; 33. Atypical pneumonia; 34. Central nervous system viral infections; 35. Common cold; 36. Genital tract and sexually transmitted infections; 37. Glandular fever-type illness; 38. Haemorrhagic fevers; 39. Infections in pregnancy, congenital and neonatal infections; 40. Respiratory virus infections; 41. Travel-related infections; 42. Viral eye infections; 43. Viral gastroenteritis; 44. Viral hepatitis; 45. Virus infections in immunocompromised patients; 46. Viral malignancies; 47. Viral rashes; 48. Viral zoonotic infections; Section 4: Laboratory Diagnosis; 49. Sending specimens to the laboratory; 50. Serological techniques; 51. Virus detection: Molecular techniques; 52. Virus detection: Non-molecular techniques; 53. Quality control and laboratory accreditation; Section 5: Patient Management; 54. Antiviral drugs; 55. Viral vaccines; 56. Infection control; 57. Occupational health; 58. Public health and pandemic preparedness; Index.
Tim Wreghitt is a retired Consultant Clinical Scientist Virologist at Addenbrooke's Hospital, Cambridge, UK, and retired Associate Lecturer at Cambridge University. He has authored over 160 peer-reviewed scientific papers and co-authored four books. Dr Wreghitt has received several awards, including an OBE for services to clinical virology and NHS Healthcare Scientist of the Year. Goura Kudesia is a retired Consultant Virologist at Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK. She was also Honorary Senior Clinical Lecturer at the University of Sheffield and Honorary Professor of Clinical Virology at Sheffield Hallam University. Dr Kudesia has published over a hundred articles and presented at numerous national and international conferences.
Reviews for Clinical and Diagnostic Virology
'This comprehensive text will provide an excellent guide to all the many health-care professionals, including those in training, who deal with patients who have, or may have, a virus infection. The rigorous structure to each chapter, with clear tables and concise factual exposition makes it easy to look up specific queries, or to learn about a specific infection in depth. This is a timely and very welcome addition to the canon of medical textbooks, given the increasing importance and relevance of clinical virology to general medicine.' Will Irving, Professor and Honorary Consultant in Virology, University of Nottingham and Nottingham University Hospitals NHS Trust 'This concise guide proves invaluable for those working within clinical virology and studying for CICE/FRCPath Part 1. As it is organised by individual viruses and clinical syndromes, it serves as both a quick reference guide and an effective teaching tool. Personally I have found the first edition of this book to be very useful throughout my career so far, so an updated second edition is most welcome!' Hayley Colton, SpR in Medical Virology/Infectious Diseases, Sheffield Teaching Hospitals NHS Foundation Trust