Chasing Men on Fire: The Story of the Search for a Pain Gene

— —

Stephen G. Waxman (Professor, Yale University School of Medicine) James E. Rothman (Sterling Professor of Cell Biology, Yale School of Medicine)

Chasing Men on Fire

The Story of the Search for a Pain Gene

Stephen G. Waxman (Professor, Yale University School of Medicine), James E. Rothman (Sterling Professor of Cell Biology, Yale School of Medicine)

$110

Hardback

Not in-store but you can order this
How long will it take?

Availability Information

We source books from suppliers in Australia and overseas. For books we don't currently have in stock, the time it takes to get them from our suppliers can vary widely - from a few days to a few months - so we check each book with each supplier to determine the expected time it will take to be supplied to us.

We then advise you accordingly. If the time taken to get any book is too long for you, you can let us know and we will cancel or adjust your order, and refund as required.

To find out the anticipated arrival time for specific items prior to ordering, please contact us by phone or email:

Phone +61 2 9264 3111, or 1800 4 BOOKS (1800 4 26657) if outside Sydney:
option 1 Abbey's Bookshop (Crime, History, Science, Kids & more) • info@abbeys.com.au
option 2 Language Book Centre (ESL & Foreign Languages) • language@abbeys.com.au
option 3 Galaxy Bookshop (Sci-fi, Fantasy, Romance, Graphic Novels) • sf@galaxybooks.com.au

QTY:

English

Massachusetts Inst of Tec
09 March 2018

Medicine; Medical genetics; Neurology & clinical neurophysiology; Pain & pain management

Series: Chasing Men on Fire

Summary
Details

"A thirty-year quest, from genes to pain-signaling neurons to people with a rare genetic disorder that makes them feel they are on fire.

Two soldiers, both with wounds injuring the same nerve, show very different responses- one is disabled by neuropathic pain, unable to touch the injured limb because even the lightest contact triggers excruciating discomfort; the other notices numbness but no pain at all. Could the difference lie in their genes? In this book, described in the foreword by Nobel Laureate James Rothman as ""so well written that it reads like a detective novel,"" Stephen Waxman recounts the search for a gene that controls pain-a search spanning more than thirty years and three continents.

The story moves from genes to pain-signaling neurons that scream when they should be silent to people with a rare genetic disorder who feel they are on fire. Waxman explains that if pain-signaling neurons are injured by trauma or disease, they can become hyperactive and send pain signals to the brain even without external stimulus. Studying the hyperactive mutant pain gene in man on fire syndrome has pointed the way to molecules that produce pain more broadly within the general population, in the rest of us. Waxman's account of the many steps that led to discovery of the pain gene tells the story behind the science, of how science happens."

By: Stephen G. Waxman (Professor Yale University School of Medicine)
Foreword by: James E. Rothman (Sterling Professor of Cell Biology Yale School of Medicine)
Imprint: Massachusetts Inst of Tec
Country of Publication: United States
Dimensions: Height: 229mm, Width: 178mm, Spine: 22mm
ISBN: 9780262037402
ISBN 10: 0262037408
Series: Chasing Men on Fire
Pages: 320
Publication Date: 09 March 2018
Recommended Age: From 18 years
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active