Characterization of Nanoparticles Intended for Drug Delivery

Jeffrey D. Clogston, Rachael M. Crist, Marina A. Dobrovolskaia , Stephan T. Stern

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English

Springer-Verlag New York Inc.
21 March 2024

Pharmacology; Medical toxicology; Nanotechnology

Series: Methods in Molecular Biology

Summary
Details

This third edition volume expands on the previous editions with new and updated discussions on the latest developments in endotoxin contamination, complex physicochemical properties, in vitro immunotoxicity traits, and in vitro drug release properties. Eight chapters in this book are dedicated to physicochemical characterization techniques and cover newer methods such as asymmetric-flow field-flow fractionation, single particle inductively coupled plasma mass spectrometry, and resistive pulse sensing. The next eighteen chapters explore the immunotoxicity of nanomaterials, including microbial contaminants such as endotoxin and beta-glucans, anti-PEG antibodies, autoimmunity, and immunosuppressive properties. The last two chapters talk about new pharmacology protocols, including a new technique to assess drug release and a tissue distribution assay using PEG immunohistochemistry. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step instructions to reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Characterization of Nanoparticles Intended for Drug Delivery, Third Edition is a valuable resource that will help both expert and novice researchers further enhance their understanding of this important and developing field.

Edited by: Jeffrey D. Clogston, Rachael M. Crist, Marina A. Dobrovolskaia, Stephan T. Stern
Imprint: Springer-Verlag New York Inc.
Country of Publication: United States
Edition: 3rd ed. 2024
Volume: 2789
Dimensions: Height: 254mm, Width: 178mm,
ISBN: 9781071637852
ISBN 10: 1071637851
Series: Methods in Molecular Biology
Pages: 324
Publication Date: 21 March 2024
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active