Cancer stem cells (CSCs) are cancer cells that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. CSCs are therefore tumorigenic (tumour-forming), perhaps in contrast to other non-tumorigenic cancer cells. CSCs may generate tumours through the stem cell processes of self-renewal and differentiation into multiple cell types. This book presents new research on cancer stem cells including mesenchymal stem cells and their role in tumour progression; Wnt signalling in colon cancer stem cells; genetic and epigenetic alterations that drive leukaemic stem cell self-renewal and others.
Edited by:
Melissa E Jordan Imprint: Nova Science Publishers Inc Country of Publication: United States Dimensions:
Height: 180mm,
Width: 260mm,
Weight: 538g ISBN:9781616689711 ISBN 10: 1616689714 Pages: 191 Publication Date:19 March 2011 Audience:
College/higher education
,
Professional and scholarly
,
Further / Higher Education
,
Undergraduate
Format:Hardback Publisher's Status: Active
Preface; Genetic & Epigenetic Alterations that Drive Leukemic Stem Cell Self-Renewal; Cancer Stem Cells in Lung Cancer: Distinct Differences between Small Cell Lung Carcinoma & Non-Small Cell Lung Carcinoma; Mesenchymal Stem Cells & their Role in Tumor Progression; Wnt Signaling in Colon Cancer Stem Cells; Stem Cells in Head & Neck Cancer: A Key to the Future?; Cancer Stem Cells & Metastasis; Human Adult Stem Cells as Targets for Cancer Stem Cells: Evolution; Oct-4 Gene & Cell-to-Cell Communication; Index.