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BRCA1 and BRCA2 Mutations: Diagnostic and Therapeutic Implications by Mani T. Valarmathi at Abbey's Bookshop,
BRCA1 and BRCA2 Mutations: Diagnostic and Therapeutic Implications
— —
Mani T. Valarmathi

BRCA1 and BRCA2 Mutations

Diagnostic and Therapeutic Implications

Mani T. Valarmathi

$272.95   $218.40

Hardback

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English
IntechOpen
18 January 2023
Medical genetics
Mutations in the BRCA1/2 genes are the most common cause of hereditary breast and ovarian cancer (HBOC), and HBOC is an autosomal dominant cancer predisposition syndrome. Individuals with HBOC have a high risk for breast and ovarian cancers and a moderate risk for other cancers, such as prostate, pancreatic, melanoma, and fallopian tube cancers. The goal of screening individuals at high risk of familial cancer is either prevention (such as a change in lifestyle or diet) or early detection of cancer. The identification of BRCA mutation carriers is important, since increased surveillance, drug therapy, and prophylactic surgery can reduce cancer-related morbidity and mortality. In recent years, there has been substantial development in BRCA-associated hereditary breast and/or breast-ovarian cancer research and its clinical applications. In this context, this book consolidates the recent advances in BRCA-related cancer biology and therapeutics, covering a wide spectrum of interrelated topics. Chapters cover a wide range of topics, such as BRCA discovery, BRCA structure and function, BRCA-associated cancers, BRCA genetic testing and counselling, and more. This book is a valuable resource not only for medical and allied health students but also for researchers, clinical and nurse geneticists, genetic counselors, and physician assistants.
Edited by:  
Imprint:   IntechOpen
Country of Publication:   United Kingdom
Dimensions:   Height: 260mm,  Width: 180mm, 
ISBN:   9781803568065
ISBN 10:   1803568062
Pages:   134
Publication Date:  
Audience:   Professional and scholarly ,  Undergraduate
Format:   Hardback
Publisher's Status:   Active

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