Boolean Networks as Predictive Models of Emergent Biological Behaviors

— —

Jordan C. Rozum (Binghamton University, State University of New York) Colin Campbell (University of Mount Union)

Boolean Networks as Predictive Models of Emergent Biological Behaviors

Jordan C. Rozum (Binghamton University, State University of New York), Colin Campbell (University of Mount Union), Eli Newby (Pennsylvania State University) , Fatemeh Sadat Fatemi Nasrollahi (Indiana University)

$238.95 $191.55

Hardback

Not in-store but you can order this
How long will it take?

Availability Information

We source books from suppliers in Australia and overseas. For books we don't currently have in stock, the time it takes to get them from our suppliers can vary widely - from a few days to a few months - so we check each book with each supplier to determine the expected time it will take to be supplied to us.

We then advise you accordingly. If the time taken to get any book is too long for you, you can let us know and we will cancel or adjust your order, and refund as required.

To find out the anticipated arrival time for specific items prior to ordering, please contact us by phone or email:

Phone +61 2 9264 3111, or 1800 4 BOOKS (1800 4 26657) if outside Sydney:
option 1 Abbey's Bookshop (Crime, History, Science, Kids & more) • info@abbeys.com.au
option 2 Language Book Centre (ESL & Foreign Languages) • language@abbeys.com.au
option 3 Galaxy Bookshop (Sci-fi, Fantasy, Romance, Graphic Novels) • sf@galaxybooks.com.au

QTY:

English

Cambridge University Press
28 March 2024

Discrete mathematics; Algebra; Mathematical modelling; Biology, life sciences

Series: Elements in the Structure and Dynamics of Complex Networks

Interacting biological systems at all organizational levels display emergent behavior. Modeling these systems is made challenging by the number and variety of biological components and interactions – from molecules in gene regulatory networks to species in ecological networks – and the often-incomplete state of system knowledge, such as the unknown values of kinetic parameters for biochemical reactions. Boolean networks have emerged as a powerful tool for modeling these systems. This Element provides a methodological overview of Boolean network models of biological systems. After a brief introduction, the authors describe the process of building, analyzing, and validating a Boolean model. They then present the use of the model to make predictions about the system's response to perturbations and about how to control its behavior. The Element emphasizes the interplay between structural and dynamical properties of Boolean networks and illustrates them in three case studies from disparate levels of biological organization.

By: Jordan C. Rozum (Binghamton University State University of New York), Colin Campbell (University of Mount Union), Eli Newby (Pennsylvania State University), Fatemeh Sadat Fatemi Nasrollahi (Indiana University), Réka Albert (Pennsylvania State University)
Imprint: Cambridge University Press
Country of Publication: United Kingdom
Weight: 222g
ISBN: 9781009478717
ISBN 10: 1009478710
Series: Elements in the Structure and Dynamics of Complex Networks
Pages: 68
Publication Date: 28 March 2024
Audience: General/trade , ELT Advanced
Format: Hardback
Publisher's Status: Active

1. Types of biological networks; 2. Modeling the dynamics of biological networks; 3. Boolean modeling of the dynamics of biological networks; 4. How to build and validate a boolean network model of a specific biological system; 5. Case study boolean systems; 6. How to analyze a boolean model: state transition graphs, attractors, and trap sets; 7. The parity-expanded network; 8. State-space compression and attractor identification using stable motifs; 9. Attractor control; Conclusions; References.