Antibody-drug conjugates (ADCs) represent a promising therapeutic approach for cancer patients by combining the antigen-targeting specificity of monoclonal antibodies (mAbs) with the cytotoxic potency of chemotherapeutic drugs. In Antibody-Drug Conjugates, expert researchers provide detailed protocols for many of the key ADC techniques necessary for working in the field. These chapters and methodologies are aimed at the key tasks necessary to identify a suitable target, properly design the mAb, the linker and the payload, as well as to conjugate them in a reproducible and scalable fashion. Written in the highly successful Methods in Molecular Biology™ format, these detailed chapters include the kind of practical implementation advice that guarantees quality results.
Authoritative and timely, Antibody-Drug Conjugates aims to further drive ADC development and thus help toward improving cancer treatments of the future.
Edited by:
Laurent Ducry Imprint: Humana Press Inc. Country of Publication: United States Edition: 2013 ed. Volume: 1045 Dimensions:
Height: 254mm,
Width: 178mm,
Spine: 23mm
Weight: 7.611kg ISBN:9781627035408 ISBN 10: 1627035400 Series:Methods in Molecular Biology Pages: 317 Publication Date:03 August 2013 Audience:
Professional and scholarly
,
Undergraduate
Format:Hardback Publisher's Status: Active