Alcohol Abuse and Liver Disease

List of Contributors vii Preface xi 1 Epidemiology of alcohol use 1 Ian Gilmore and William Gilmore 2 Epidemiology of alcohol]related liver disease 11 Ed Britton and Martin Lombard 3 Alcoholism: diagnosis and natural history in the context of medical disease 23 Thomas P. Beresford Narin Wongngamnit and Benjamin A. Temple 4 Alcohol and other substance misuse 35 John B. Saunders 5 Risk factors for alcohol]related liver disease 47 Stuart Kendrick and Chris Day 6 Mechanisms of alcohol toxicity 55 Guruprasad P. Aithal and Jane I. Grove 7 Extrahepatic manifestations of alcohol excess 65 Karl]Heinz Schulz Sandra van Eckert and Jens Reimer 8 Patterns of alcohol]associated liver damage 79 Peter Hayes and Michael Williams 9 Cofactors and alcohol]related liver disease 87 John G. O’Grady 10 Impact of alcohol and liver disease on prescribing 91 Richard Parker and Amanda Smith 11 Psychiatric examination of liver transplant patients with alcohol use disorders 99 Robert M. Weinrieb and Omair Abbasi 12 Abnormal liver tests in the context of alcohol excess 109 James Ferguson 13 Biochemical determination of alcohol consumption 113 Friedrich Martin Wurst Natasha Thon Wolfgang Weinmann Michel Yegles Jessica Wong and Ulrich W. Preuss 14 The role of histology 123 Desley A.H. Neil 15 General assessment and management 135 Patrizia Burra and Giacomo Germani 16 Brief alcohol interventions 147 Stephanie Scott and Eileen Kaner 17 Alcohol withdrawal syndrome: diagnosis and treatment 155 Julie Taub and Thomas P. Beresford 18 Psychosocial treatments of alcohol use disorders 165 Terry D. Schneekloth 19 Pharmacologic interventions 175 Renata Yang and Marian Fireman 20 Treatment of extrahepatic manifestations of alcohol abuse 187 Joaquim Fernandez]Sola 21 Treatment of liver disease 197 James Neuberger 22 Treatment of alcoholic hepatitis 203 Mark Thursz and Stephen Atkinson 23 Liver transplantation in people with alcohol]related liver disease 215 Santiago Tome and Michael R. Lucey 24 Future directions: the need for early identification and intervention for patients with excessive alcohol use 223 Andrea DiMartini Shari Rogal and Stephen Potts Index 235