A Foundation Course for College Organic Chemistry

B. S. Balaji (Jawaharlal Nehru University, India)

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English

CRC Press
22 August 2024

Environmental medicine; Organic chemistry; Life sciences: general issues; Biochemistry; Biotechnology

To understand and improve the underlying principles that govern how organic reactions occur, A Foundation Course for College Organic Chemistry follows a brick-by-brick building approach. Emphasis is given to interrelating experimental facts and findings with predictions (mechanism) and inferences (results). Discussions focus on clarifying how complex organic reactions occur, which is based on electronegativity differences, movement of electrons (through σ framework or π bonds), and addition or removal of atoms (hydrogen, halogens) or groups (hydroxy, amino).

The book begins with simple rules governing the deconstruction of reactions and applies them to explain how esterification, amide, and cyanide hydrolysis reactions proceed. The importance of stereochemistry (used in drug development, biology, and medicine), aromatic electrophilic and nucleophilic substitutions, reaction kinetics, and dynamics is explained with suitable examples.

Features:

A systematic and structured approach is used to study all aspects of reactive intermediates (generation, structure, geometry, and reactions of carbocations, carbanions, and carbon-free radicals) This book incorporates scientific methods to deduce reaction mechanisms with simple and relevant explanations, and limitations A proper explanation is given to understand the influence of functional groups on the stability and reactivity of intermediates, pKa, HSAB principles, structure-activity relations, and how these can be exploited in organic chemistry Information is presented in an accessible way for students, teachers, researchers, and scientists

By: B. S. Balaji (Jawaharlal Nehru University India)
Imprint: CRC Press
Country of Publication: United Kingdom
Dimensions: Height: 280mm, Width: 210mm,
Weight: 648g
ISBN: 9781032631141
ISBN 10: 1032631147
Pages: 246
Publication Date: 22 August 2024
Audience: College/higher education , Professional and scholarly , Primary , Undergraduate
Format: Hardback
Publisher's Status: Active

1 Deconstruction of organic reactions 2 Geometric isomerism 3 Conformational isomerism: open chain and cyclic systems 4 Basics of Symmetry elements and point groups 5 Stereochemical conventions and topicity 6 Chiroptical properties 7 Stereochemical reactions 8 Aromaticity and polyaromatic compounds 9 Aromatic electrophilic and nucleophilic substitutions 10 Reaction dynamics and reaction kinetics 11 Reactive intermediates: carbocations 12 Reactive intermediates: carbanions 13 Reactive intermediates: Free radicals 14 Reactive intermediates: Carbenes and nitrenes 15 Carbon-carbon bond formation using carbon nucleophiles: enolates, enamines and enol ethers 16 Name reactions

B. S. Balaji is Chairperson of Special Center for E‑learning and a Professor in the School of Biotechnology at Jawaharlal Nehru University. He is an award‑winning chemistry educator, has published various research papers, has developed 3D‑printed Braille models to teach chemistry concepts to BLV students, is a resource person (ICT) for Malaviya Mission Teacher training program of UGC, is a Member of Technical Expert Committee, and is in the Interface Expert Committee to assess the NON‑SWAYAM Learning Platforms of HEI for UGC‑DEB.