A Biophysical Approach to Investigate the Interactions of Cyclooxygenase Inhibitors with Human Hemoglobin...

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Paromita Seal

A Biophysical Approach to Investigate the Interactions of Cyclooxygenase Inhibitors with Human Hemoglobin and Erythrocyte

Paromita Seal

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English

Independent Publisher
07 October 2024

Summary
Details

For last few decades, drug-protein interaction plays a crucial role in the transport and distribution of various molecules in the physiological system. Interaction between ligand and biomolecules especially protein (3) has motivated interdisciplinary research concerning both synthetic and analytical biochemists to ascertain the biological function of small molecules. However, blood proteins enact the most active and assorted roles in cells by delivering diverse functions including the control of biochemical reactions, providing intracellular and extracellular scaffolding, transport of different bio-molecules, controlling enzymatic action, and building the immune system (4). Generally, drugs are administered through several routs like, oral, sublingual, buccal, topical, parenteral, transdermal, subcutaneous, intramuscular, intravenous, vaginal and rectal. After being distributed in the circulating blood drugs bind to their carrier proteins in the plasma in varying degrees. In common, such binding is undergoes reversible and rapid equilibrium process between bound and free molecular species.

By: Paromita Seal
Imprint: Independent Publisher
Dimensions: Height: 279mm, Width: 216mm, Spine: 7mm
Weight: 331g
ISBN: 9798227728708
Pages: 136
Publication Date: 07 October 2024
Audience: General/trade , ELT Advanced
Format: Paperback
Publisher's Status: Active